Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAPGEF3 | O95398 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1405492 | 0.90 | RAPGEF3 (0.43) | L3MBTL1GAAMAPTALDH1A1RAPGEF3 | |
| SCHEMBL4411793 | 0.84 | L3MBTL1 (0.41) | L3MBTL1GAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4411790 | 0.84 | L3MBTL1 (0.41) | L3MBTL1GAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7088222 | 0.82 | ALDH1A1 (0.43) | GAAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1405519 | 0.81 | GAA (0.40) | GAAMAPTALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1877841 | 0.80 | TSHR (0.51) | MAPTRAPGEF3SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29176936 | 0.75 | ABCB1 (0.41) | GAAMAPTALDH1A1SMN1; SMN2ABCB1 | |
| SCHEMBL9416789 | 0.75 | ALDH1A1 (0.46) | L3MBTL1GAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30929805 | 0.73 | TDP1 (0.41) | GAAALDH1A1SMN1; SMN2TDP1MEN1 | |
| SCHEMBL30929806 | 0.73 | ALDH1A1 (0.42) | GAAMAPTALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935674-B2 | Indole derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-05-03 | — | — | US | disclosed |
| CN-101111492-B | Indole derivatives | TANABE SEIYAKU CO | 2010-09-22 | — | — | CN | disclosed |
| US-20090258921-A1 | INDOLE DERIVATIVES | NOMURA SUMIHIRO | 2009-10-15 | — | — | US | disclosed |
| US-20080119422-A1 | Indole Derivatives | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-05-22 | — | — | US | disclosed |
| CN-101111492-A | Indole derivatives | TANABE SEIYAKU CO (JP) | 2008-01-23 | — | — | CN | disclosed |
| EP-1863798-A1 | INDOLE DERIVATIVES | Mitsubishi Tanabe Pharma Corporation (JP) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006080577-A1 | INDOLE DERIVATIVES | TANABE SEIYAKU CO., LTD. (JP) | 2006-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258921-A1 | INDOLE DERIVATIVES | IDO1, TPH1, NAT1 | L3MBTL1 2915/4885GAA 4689/4885MAPT 1632/4885 |
| US-20080119422-A1 | Indole Derivatives | IDO1, TPH1, NAT1 | L3MBTL1 2915/4885GAA 4689/4885MAPT 1632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.