Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19413426 | 0.84 | HSD17B10 (0.39) | HSD17B10TSHR | |
| SCHEMBL17232740 | 0.77 | ALDH1A1 (0.30) | HSD17B10ALDH1A1MAPTHPGD | |
| SCHEMBL17229783 | 0.73 | CYP2C19 (0.31) | — | |
| SCHEMBL13948699 | 0.71 | HCAR2 (0.44) | HSD17B10MAPTHPGDTSHR | |
| SCHEMBL14048246 | 0.71 | HCAR2 (0.44) | HSD17B10ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL16517262 | 0.70 | HCAR2 (0.57) | TSHR | |
| SCHEMBL19297183 | 0.69 | — | — | |
| SCHEMBL19153230 | 0.67 | CYP2C19 (0.33) | MAPTHPGD | |
| SCHEMBL21388568 | 0.67 | HSD17B10 (0.36) | HSD17B10TSHR | |
| SCHEMBL21388626 | 0.66 | HCAR2 (0.35) | HSD17B10ALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787453-B2 | Octahydropyrrolopyrroles their preparation and use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2020-09-29 | — | — | US | disclosed |
| US-20190290771-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO, INC. | 2019-09-26 | — | — | US | disclosed |
| US-9637450-B2 | Octahydrocyclopentapyrroles, their preparation and use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190290771-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | CD44, MSN, AS3MT | HSD17B10 3435/4885ALDH1A1 2151/4885MAPT 1162/4885 |
| US-10787453-B2 | Octahydropyrrolopyrroles their preparation and use | QDPR, DPYD, DHPS | HSD17B10 2984/4885ALDH1A1 875/4885MAPT 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.