Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 3/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 9/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18800048 | 0.88 | SPR (0.52) | SPRMTNR1AMTNR1BPTGS1GAA | |
| SCHEMBL18800024 | 0.86 | SPR (0.50) | SPRMTNR1AMTNR1BPTGS1PTGS2 | |
| SCHEMBL18800012 | 0.86 | MTNR1A (0.55) | MTNR1AMTNR1B | |
| SCHEMBL18800080 | 0.79 | MTNR1A (0.46) | MTNR1AMTNR1B | |
| SCHEMBL18800043 | 0.76 | MTNR1A (0.41) | SPRMTNR1AMTNR1B | |
| SCHEMBL18222512 | 0.75 | PTGDR2 (0.51) | SPRMTNR1BKDM4E | |
| SCHEMBL18800052 | 0.74 | MTNR1A (0.64) | MTNR1AMTNR1BKDM4EHSD17B10 | |
| SCHEMBL18800026 | 0.73 | MTNR1A (0.51) | MTNR1AMTNR1BPTGS1PTGS2PLA2G2A | |
| SCHEMBL28100773 | 0.72 | SPR (0.48) | SPRMTNR1BPLA2G2A | |
| SCHEMBL12720824 | 0.71 | SPR (1.00) | SPRMTNR1AMTNR1BPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9637451-B2 | Indole compound | ASTELLAS PHARMA INC. (JP) | 2017-05-02 | — | — | US | disclosed |