Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565156 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KMT2ALMNAGAAMEN1 | |
| SCHEMBL39108 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KMT2AKDM4ELMNAGAA | |
| SCHEMBL2723103 | 0.73 | GLA (0.57) | ALDH1A1KMT2AKDM4ELMNAGAA | |
| SCHEMBL31497268 | 0.73 | ALDH1A1 (0.45) | ALDH1A1KMT2ALMNAGAAMEN1 | |
| SCHEMBL9818045 | 0.72 | ESR1 (0.44) | ALDH1A1KMT2AKDM4ELMNAMEN1 | |
| Benzene SCHEMBL27985319 | 0.72 | ESR1 (0.44) | ALDH1A1KMT2AKDM4ELMNAMEN1 | |
| SCHEMBL39946 | 0.72 | ESR1 (0.44) | ALDH1A1KMT2AKDM4ELMNAMEN1 | |
| SCHEMBL11635311 | 0.70 | ALDH1A3 (0.42) | ALDH1A1KMT2AKDM4ELMNAGAA | |
| SCHEMBL6406224 | 0.70 | CA12 (0.45) | ALDH1A1KMT2AKDM4ELMNAGAA | |
| Water SCHEMBL10786878 | 0.70 | ESR1 (0.43) | ALDH1A1KMT2AKDM4ELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947831-B2 | Sulfoxides or sulfones grafted onto polymers | BASF SE Ludwigshafen (DE) | 2011-05-24 | — | — | US | disclosed |
| US-20070015870-A1 | Sulfoxides or sulfones grafted onto polymers | CIBA CORPORATION | 2007-01-18 | — | — | US | disclosed |