Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 2/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PTPRG | P23470 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18131143 | 0.98 | LMNA (0.44) | LMNAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL1031987 | 0.94 | DHODH (0.43) | LMNAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL2871268 | 0.85 | GAA (0.42) | LMNAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL3127871 | 0.82 | BCAT2 (0.46) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL5501967 | 0.82 | GAA (0.40) | LMNAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL10328560 | 0.82 | ALDH1A1 (0.43) | LMNAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL27938634 | 0.80 | ALDH1A1 (0.49) | LMNAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL4002783 | 0.79 | LMNA (0.55) | LMNAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL20825514 | 0.77 | KMT2A (0.50) | LMNAKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL3919584 | 0.76 | MEN1 (0.48) | LMNAKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446298-B2 | Pyrimidine derivatives | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-09-20 | — | — | US | claimed |
| EP-3928836-B1 | N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-09-18 | — | — | EP | disclosed |
| US-12011444-B2 | N-substituted indole derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-18 | — | — | US | disclosed |
| US-11839613-B2 | Pyrimidine derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-12-12 | — | — | US | disclosed |
| US-11712438-B2 | Phenyl derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-08-01 | — | — | US | disclosed |
| WO-2023138684-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO , INC. (US) | 2023-07-27 | — | — | WO | disclosed |
| US-11446298-B2 | Pyrimidine derivatives | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-09-20 | — | — | US | disclosed |
| EP-3625227-B1 | BENZOFURANE AND BENZOTHIOPHENE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-09-14 | — | — | EP | disclosed |
| EP-3377483-B9 | N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-08-03 | — | — | EP | disclosed |
| US-20220175775-A1 | N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-06-09 | — | — | US | disclosed |
| US-7501530-B2 | Trifluoromethyl-thiophene carboxylic acid aniledes and use thereof as fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2009-03-10 | — | — | US | disclosed |
| US-20060172891-A1 | Trifluoromethyl-thiophene carboxylic acid aniledes and use thereof as fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2006-08-03 | — | — | US | disclosed |
| US-20060172891-A1 | Trifluoromethyl-thiophene carboxylic acid aniledes and use thereof as fungicides | BASF AKTIENGESELLSCHAFT (DE) | 2006-08-03 | — | — | US | disclosed |
| CN-1764657-A | Trifluoromethyl-thiophene carboxylic acid anilides and use thereof as fungicides. | BASF AG (DE) | 2006-04-26 | — | — | CN | disclosed |
| CN-1764657-A | Trifluoromethyl-thiophene carboxylic acid anilides and use thereof as fungicides. | BASF AG (DE) | 2006-04-26 | — | — | CN | disclosed |
| CN-1764657-A | Trifluoromethyl-thiophene carboxylic acid anilides and use thereof as fungicides. | BASF AG (DE) | 2006-04-26 | — | — | CN | disclosed |
| EP-1608637-A1 | TRIFLUOROMETHYL-THIOPHENE CARBOXYLIC ACID ANILIDES AND USE THEREOF AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-28 | — | — | EP | disclosed |
| EP-1608637-A1 | TRIFLUOROMETHYL-THIOPHENE CARBOXYLIC ACID ANILIDES AND USE THEREOF AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004085419-A1 | TRIFLUOROMETHYL-THIOPHENE CARBOXYLIC ACID ANILIDES AND USE THEREOF AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-10-07 | — | — | WO | disclosed |
| WO-2004085419-A1 | TRIFLUOROMETHYL-THIOPHENE CARBOXYLIC ACID ANILIDES AND USE THEREOF AS FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060172891-A1 | Trifluoromethyl-thiophene carboxylic acid aniledes and use thereof as fungicides | AS3MT, GABBR1, TH | LMNA 3934/4885KMT2A 667/4885MEN1 1644/4885 |
| US-11712438-B2 | Phenyl derivatives as PGE2 receptor modulators | PTGER1, PTGER4, PTGER2 | LMNA 4359/4885KMT2A 1790/4885MEN1 4151/4885 |
| US-20220175775-A1 | N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | PTGER1, PTGER4, PTGER2 | LMNA 3249/4885KMT2A 2262/4885MEN1 2595/4885 |
| US-11839613-B2 | Pyrimidine derivatives as PGE2 receptor modulators | PTGER1, PTGER4, PTGER2 | LMNA 4601/4885KMT2A 2391/4885MEN1 4485/4885 |
| US-12011444-B2 | N-substituted indole derivatives as PGE2 receptor modulators | PTGER1, PTGER4, PTGER2 | LMNA 3249/4885KMT2A 2262/4885MEN1 2595/4885 |
| US-11446298-B2 | Pyrimidine derivatives | PTGER1, PTGER4, PTGER2 | LMNA 4541/4885KMT2A 2332/4885MEN1 4381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.