SCHEMBL1880241

SCHEMBL1880241

COC(CC(=O)c1ccccc1)OC

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.62
L3MBTL1 Q9Y468 3/20 0.57
POLB P06746 2/20 0.57
HTT P42858 2/20 0.57
NPSR1 Q6W5P4 1/20 0.57
TSHR P16473 2/20 0.57
NPC1 O15118 3/20 0.56
MEN1 O00255 2/20 0.56
ALDH1A1 P00352 4/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
LMNA P02545 2/20 0.50
MAPT P10636 2/20 0.50
HPGD P15428 2/20 0.50
MAPK1 P28482 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
KDM4E B2RXH2 1/20 0.50
CYP3A4 P08684 1/20 0.50
ALOX15 P16050 1/20 0.50
CES1 P23141 1/20 0.50
ATM Q13315 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10884799 0.82 KMT2A (0.61) KMT2AL3MBTL1POLBHTTNPSR1
SCHEMBL8791143 0.82 GSK3B (0.52) KMT2AL3MBTL1POLBHTTNPC1
SCHEMBL105978 0.81 GSK3B (0.52) KMT2AHTTNPSR1NPC1MEN1
SCHEMBL9155651 0.81 KMT2A (0.62) KMT2AL3MBTL1POLBHTTNPSR1
SCHEMBL8038291 0.81 KMT2A (0.59) KMT2AL3MBTL1POLBHTTNPSR1
SCHEMBL9431583 0.81 L3MBTL1 (0.52) KMT2AL3MBTL1POLBHTTNPSR1
SCHEMBL15673419 0.79 KMT2A (0.57) KMT2AL3MBTL1POLBHTTNPSR1
SCHEMBL91606 0.79 L3MBTL1 (0.59) KMT2AL3MBTL1POLBHTTNPSR1
SCHEMBL31544408 0.79 KMT2A (0.57) KMT2AL3MBTL1POLBHTTNPSR1
SCHEMBL9751251 0.78 KMT2A (0.70) KMT2AL3MBTL1POLBHTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400784-A1 Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition LG CHEM, LTD. (KR) 2024-12-05 US disclosed
US-7939674-B2 Process for producing an aromatic unsaturated compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-05-10 US disclosed
EP-2219600-A1 TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF STIEFEL LABORATORIES, INC. (US) 2010-08-25 EP disclosed
US-7700642-B2 Process for producing an aromatic unsaturated compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-20 US disclosed
WO-2009067095-A1 TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF STIEFEL LABORATORIES, INC. (US) 2009-05-28 WO disclosed
US-20090111999-A1 PROCESS FOR PRODUCING AN AROMATIC UNSATURATED COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-30 US disclosed
US-20080221337-A1 Process for Producing an Aromatic Unsaturated Compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-11 US disclosed
EP-1487770-B1 FORMATION OF NEOLIGNAN BY DDQ MEDIATED DIMERISATION OF DIHYDROASARONE COUNCIL SCIENT IND RES (IN) 2007-12-12 EP disclosed
EP-1786749-A1 ZEOLITE BASED CATALYTIC PROCESS FOR PREPARATION OF ACYLATED AROMATIC ETHERS COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2007-05-23 EP disclosed
US-20070100157-A1 Zeolite based catalytic process for preparation of acylated aromatic ethers COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (AU) 2007-05-03 US disclosed
US-20060041171-A1 Zeolite based catalytic process for preparation of acylated aromatic ethers COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2006-02-23 US disclosed
WO-2006016197-A1 ZEOLITE BASED CATALYTIC PROCESS FOR PREPARATION OF ACYLATED AROMATIC ETHERS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2006-02-16 WO disclosed
US-6969778-B2 DDQ mediated one step dimerization of β-asarone or β-asarone rich Acorus calamus oil in the formation of novel neolignan COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2005-11-29 US disclosed
EP-1487770-A1 FORMATION OF NEOLIGNAN BY DDQ MEDIATED DIMERISATION OF DIHYDROASARONE Council of Scientific and Industrial Research;an Indian Reg. body incorporated under Reg. of Societies Act (Act XXI of 1860) (IN) 2004-12-22 EP disclosed
US-20040049085-A1 DDQ mediated one step dimerisation of beta-asarone or beta-asarone rich acorus calamus oil in the formation of novel neolignan COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH 2004-03-11 US disclosed
US-20030187306-A1 DDQ mediated one step dimerisation of beta-asarone or beta-asarone rich acorus calamus oil in the formation of novel neolignan COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH 2003-10-02 US disclosed
WO-2003080551-A1 FORMATION OF NEOLIGNAN BY DDQ MEDIATED DIMERISATION OF DIHYDROASARONE COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-10-02 WO disclosed
US-5250533-A Fungicidal pyridinylpyrimidines BAYER AKTIENGESELLSCHAFT (DE) 1993-10-05 US disclosed
EP-0515942-A1 Use of pyridinylpyrimidine derivatives for the protection of technical materials BAYER AG (DE) 1992-12-02 EP disclosed
EP-0431424-A2 Pyridinylpyrimidin derivatives BAYER AG (DE) 1991-06-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040049085-A1 DDQ mediated one step dimerisation of beta-asarone or beta-asarone rich acorus calamus oil in the formation of novel neolignan DHPS, PTGES, PTGIS KMT2A 2954/4885L3MBTL1 4731/4885POLB 347/4885
US-20070100157-A1 Zeolite based catalytic process for preparation of acylated aromatic ethers KDM4E, ACE, CAT KMT2A 79/4885L3MBTL1 3736/4885POLB 905/4885
US-20030187306-A1 DDQ mediated one step dimerisation of beta-asarone or beta-asarone rich acorus calamus oil in the formation of novel neolignan DHPS, PTGES, PTGIS KMT2A 2954/4885L3MBTL1 4731/4885POLB 347/4885
US-20080221337-A1 Process for Producing an Aromatic Unsaturated Compound AHR, AR, ARSA KMT2A 2146/4885L3MBTL1 4528/4885POLB 2861/4885
US-20090111999-A1 PROCESS FOR PRODUCING AN AROMATIC UNSATURATED COMPOUND AHR, AR, ARSA KMT2A 2146/4885L3MBTL1 4528/4885POLB 2861/4885
US-20060041171-A1 Zeolite based catalytic process for preparation of acylated aromatic ethers KDM4E, ACE, CAT KMT2A 78/4885L3MBTL1 3683/4885POLB 915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.