Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | PON1 | P27169 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL869646 | 0.98 | NPSR1 (0.51) | NPSR1MEN1APAF1NPC1PLA2G1B | |
| Bromide SCHEMBL2835015 | 0.97 | NPSR1 (0.54) | NPSR1MEN1APAF1NPC1PLA2G1B | |
| SCHEMBL12558221 | 0.94 | NPSR1 (0.54) | NPSR1MEN1APAF1NPC1PLA2G1B | |
| SCHEMBL2832102 | 0.92 | NPSR1 (0.46) | NPSR1MEN1APAF1NPC1PLA2G1B | |
| SCHEMBL21314161 | 0.92 | NPSR1 (0.46) | NPSR1MEN1APAF1NPC1PLA2G1B | |
| Hydrochloric Acid SCHEMBL8137482 | 0.90 | KMT2A (0.45) | NPSR1MEN1APAF1NPC1PLA2G1B | |
| SCHEMBL21314159 | 0.89 | MAPT (0.43) | NPSR1MEN1APAF1NPC1PLA2G1B | |
| SCHEMBL925001 | 0.88 | KMT2A (0.46) | NPSR1MEN1APAF1NPC1PLA2G1B | |
| Trifluoromethanesulfonic Acid SCHEMBL2830949 | 0.84 | NPSR1 (0.40) | NPSR1MEN1APAF1NPC1PLA2G1B | |
| SCHEMBL17316661 | 0.80 | MEN1 (0.51) | NPSR1MEN1APAF1NPC1PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8083945-B2 | Fluid storage and purification method and system | MATHESON TRI-GAS, INC. (US) | 2011-12-27 | — | — | US | claimed |
| US-20100223208-A1 | FLUID STORAGE AND PURIFICATION METHOD AND SYSTEM | MATHESON TRI-GAS, INC. (US) | 2010-09-02 | — | — | US | claimed |
| US-11312852-B2 | Method for preparing graft copolymer complex, graft copolymer complex, and thermoplastic resin composition comprising graft copolymer complex | LG CHEM, LTD. (KR) | 2022-04-26 | — | — | US | disclosed |
| EP-3533810-B1 | METHOD FOR PREPARING GRAFT COPOLYMER COMPLEX, GRAFT COPOLYMER COMPLEX, AND THERMOPLASTIC RESIN COMPOSITION COMPRISING THE GRAFT COPOLYMER COMPLEX | LG CHEMICAL LTD (KR) | 2021-04-21 | — | — | EP | disclosed |
| EP-3533810-A1 | METHOD FOR PRODUCING GRAFT COPOLYMER COMPOSITE, GRAFT COPOLYMER COMPOSITE, AND THERMOPLASTIC RESIN COMPOSITION INCLUDING SAME | LG Chem, Ltd. (KR) | 2019-09-04 | — | — | EP | disclosed |
| US-8083945-B2 | Fluid storage and purification method and system | MATHESON TRI-GAS, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-7955416-B2 | Polymerized polymeric fluid storage and purification method and system | MATHESON TRI-GAS, INC. (US) | 2011-06-07 | — | — | US | disclosed |
| US-7938968-B2 | storing and dispensing a fluid includes providing a vessel configured for selective dispensing of the fluid therefrom. The vessel contains an ionic liquid therein. The fluid is contacted with the ionic liquid for take-up of the fluid by the ionic liquid. | MATHESON TRI GAS (US) | 2011-05-10 | — | — | US | disclosed |
| US-7896954-B2 | storing and dispensing a fluid includes providing a vessel configured for selective dispensing of the fluid therefrom; The fluid is contacted with the ionic liquid for take-up of the fluid by the ionic liquid | MATHESON TRI-GAS, INC. (US) | 2011-03-01 | — | — | US | disclosed |
| US-20100223208-A1 | FLUID STORAGE AND PURIFICATION METHOD AND SYSTEM | MATHESON TRI-GAS, INC. (US) | 2010-09-02 | — | — | US | disclosed |
| US-20100140175-A1 | POLYMERIZED POLYMERIC FLUID STORAGE AND PURIFICATION METHOD AND SYSTEM | MATHESON TRI-GAS (US) | 2010-06-10 | — | — | US | disclosed |
| US-20060226072-A1 | Fluid storage and purification method and system | MATHESON TRI-GAS | 2006-10-12 | — | — | US | disclosed |
| US-20060226074-A1 | Fluid storage and purification method and system | MATHESON TRI-GAS | 2006-10-12 | — | — | US | disclosed |
| US-20060226073-A1 | Fluid storage and purification method and system | MATHESON TRI-GAS | 2006-10-12 | — | — | US | disclosed |
| WO-2006063656-A1 | METHOD FOR PRODUCING ONIUM SALTS COMPRISING ALKYL ANIONS OR ARYL SULFONATE ANIONS OR ALKYL ANIONS OR ARYL CARBOXYLATE ANIONS HAVING A LOW HALIDE CONTENT | MERCK PATENT GMBH (DE) | 2006-06-22 | — | — | WO | disclosed |
| US-7005282-B2 | Enzymes coated with ionic liquid | POSCO AND POSTECH FOUNDATION (KR) | 2006-02-28 | — | — | US | disclosed |
| EP-1468083-A1 | ENZYMES COATED WITH IONIC LIQUID | Posco (KR) | 2004-10-20 | — | — | EP | disclosed |
| CN-1498268-A | Enzymes coated with ionic liquid | POSCO公司 | 2004-05-19 | — | — | CN | disclosed |
| US-20040087462-A1 | Enzymes cooated with ionic liquid | POSCO (KR) | 2004-05-06 | — | — | US | disclosed |
| WO-2003057871-A1 | ENZYMES COATED WITH IONIC LIQUID | POSCO (KR) | 2003-07-17 | — | — | WO | disclosed |