Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL869646 | 0.90 | NPSR1 (0.51) | MAPTNPSR1MEN1APAF1NPC1 | |
| Trifluoromethanesulfonic Acid SCHEMBL2830949 | 0.90 | NPSR1 (0.40) | MAPTNPSR1MEN1APAF1NPC1 | |
| Bromide SCHEMBL2835015 | 0.89 | NPSR1 (0.54) | MAPTNPSR1MEN1APAF1NPC1 | |
| Hydrochloric Acid SCHEMBL1880315 | 0.89 | NPSR1 (0.50) | MAPTNPSR1MEN1APAF1NPC1 | |
| SCHEMBL12558221 | 0.86 | NPSR1 (0.54) | MAPTNPSR1MEN1APAF1NPC1 | |
| SCHEMBL21314161 | 0.85 | NPSR1 (0.46) | MAPTNPSR1MEN1APAF1NPC1 | |
| SCHEMBL2832102 | 0.85 | NPSR1 (0.46) | MAPTNPSR1MEN1APAF1NPC1 | |
| SCHEMBL17431224 | 0.83 | PON1 (0.43) | MAPTNPSR1MEN1APAF1NPC1 | |
| SCHEMBL925001 | 0.81 | KMT2A (0.46) | MAPTNPSR1MEN1APAF1NPC1 | |
| Hydrochloric Acid SCHEMBL8137482 | 0.79 | KMT2A (0.45) | MAPTNPSR1MEN1APAF1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11312852-B2 | Method for preparing graft copolymer complex, graft copolymer complex, and thermoplastic resin composition comprising graft copolymer complex | LG CHEM, LTD. (KR) | 2022-04-26 | — | — | US | disclosed |
| CN-110198962-B | Method for preparing graft copolymer composite, and thermoplastic resin composition comprising the same | 株式会社LG化学 | 2022-01-07 | — | — | CN | disclosed |
| EP-3533810-B1 | METHOD FOR PREPARING GRAFT COPOLYMER COMPLEX, GRAFT COPOLYMER COMPLEX, AND THERMOPLASTIC RESIN COMPOSITION COMPRISING THE GRAFT COPOLYMER COMPLEX | LG CHEMICAL LTD (KR) | 2021-04-21 | — | — | EP | disclosed |
| EP-3533810-A1 | METHOD FOR PRODUCING GRAFT COPOLYMER COMPOSITE, GRAFT COPOLYMER COMPOSITE, AND THERMOPLASTIC RESIN COMPOSITION INCLUDING SAME | LG Chem, Ltd. (KR) | 2019-09-04 | — | — | EP | disclosed |