Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | HCK | P08631 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.46 |
| ▸ | MTOR | P42345 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.46 |
| ▸ | PRKDC | P78527 | 2/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.46 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.44 |
| ▸ | BUB1 | O43683 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819797 | 1.00 | PIK3CD (0.46) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL7218364 | 0.88 | BUB1 (0.42) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL30711678 | 0.88 | BUB1 (0.42) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL3269495 | 0.84 | PIK3CD (0.47) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL1273077 | 0.84 | HTR6 (0.49) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL31424162 | 0.84 | ACLY (0.43) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL30147588 | 0.84 | ACLY (0.43) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL15218078 | 0.83 | MAP2K4 (0.45) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL312329 | 0.82 | PIK3CD (0.51) | PIK3CDABL1EGFRHCKSRC | |
| SCHEMBL2006239 | 0.82 | OXER1 (0.50) | PIK3CDABL1EGFRHCKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137341-A1 | FLUORINATION METHOD | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-05-18 | — | — | US | disclosed |
| US-20170121300-A1 | METHOD OF FLUORINATION USING IODONIUM YLIDES | THE GENERAL HOSPITAL CORPORATION | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121300-A1 | METHOD OF FLUORINATION USING IODONIUM YLIDES | FLI1, ABL1, PFAS | PIK3CD 1375/4885ABL1 2/4885EGFR 635/4885 |
| US-20170137341-A1 | FLUORINATION METHOD | F13B, PPARG, PGC | PIK3CD 2973/4885ABL1 1196/4885EGFR 705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.