Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.43 |
| ▸ | CTSL | P07711 | 4/20 | 0.43 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28951054 | 0.87 | CTSK (0.49) | CTSKCTSLCTSBLMNACTSS | |
| SCHEMBL7531427 | 0.83 | CTSK (0.50) | CTSKCTSLCTSBLMNACTSS | |
| SCHEMBL28607722 | 0.78 | LMNA (0.39) | CTSKCTSLCTSBLMNACTSS | |
| SCHEMBL1725213 | 0.74 | LMNA (0.41) | CTSKCTSLCTSBLMNACTSS | |
| SCHEMBL20959847 | 0.72 | CTSK (0.52) | CTSKCTSLCTSBLMNACTSS | |
| SCHEMBL10631882 | 0.71 | CTSK (0.49) | CTSKCTSLCTSBLMNACTSS | |
| SCHEMBL28455482 | 0.70 | ALDH1A1 (0.41) | LMNAALDH1A1 | |
| SCHEMBL7648047 | 0.70 | CTSK (0.49) | CTSKCTSLCTSBLMNACTSS | |
| SCHEMBL3857434 | 0.69 | CTSK (0.42) | CTSKCTSLCTSBLMNACTSS | |
| SCHEMBL27823223 | 0.69 | CTSK (0.49) | CTSKCTSLCTSBCTSSMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939528-B2 | Heterocycle compounds | GLAXOSMITHKLINE LLC (US) | 2011-05-10 | — | — | US | disclosed |