Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18810573 | 0.80 | CES2 (0.37) | CES2CES1ALDH1A1HDAC8HDAC6 | |
| SCHEMBL11560406 | 0.80 | CES2 (0.44) | CES2CES1ALDH1A1HDAC8HDAC6 | |
| SCHEMBL7215686 | 0.80 | CES2 (0.44) | CES2CES1ALDH1A1HDAC8HDAC6 | |
| SCHEMBL11517448 | 0.78 | CES2 (0.38) | CES2CES1ALDH1A1HDAC8HDAC6 | |
| SCHEMBL11559349 | 0.78 | CES2 (0.38) | CES2CES1ALDH1A1HDAC8HDAC6 | |
| SCHEMBL9513379 | 0.78 | ALDH1A1 (0.34) | CES2CES1ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL9129938 | 0.78 | CES2 (0.38) | CES2CES1ALDH1A1HDAC8HDAC6 | |
| SCHEMBL9089559 | 0.77 | MEN1 (0.40) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL9088517 | 0.75 | CES2 (0.34) | CES2CES1ALDH1A1HDAC8HDAC6 | |
| SCHEMBL1536111 | 0.75 | MMP1 (0.43) | CES2CES1ALDH1A1TSHREPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170121325-A1 | FUSED IMIDAZOLE DERIVATIVES AS IDO/TDO INHIBITORS | FELIQS CORPORATION (JP) | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170121325-A1 | FUSED IMIDAZOLE DERIVATIVES AS IDO/TDO INHIBITORS | IDO1, IDO2, TDO2 | CES2 2288/4885CES1 1518/4885ALDH1A1 1116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.