Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 1/20 | 1.00 |
| ▸ | APP | P05067 | 3/20 | 0.69 |
| ▸ | TTR | P02766 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.69 |
| ▸ | DPP4 | P27487 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.69 |
| ▸ | CA12 | O43570 | 1/20 | 0.69 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | CA1 | P00915 | 1/20 | 0.69 |
| ▸ | CA2 | P00918 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | MMP1 | P03956 | 1/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29364807 | 1.00 | IAPP (1.00) | IAPPPTGS1APPTTRKDM4E | |
| SCHEMBL1881133 | 1.00 | IAPP (1.00) | IAPPPTGS1APPTTRKDM4E | |
| Hispolon SCHEMBL15917284 | 0.85 | IAPP (0.74) | IAPPPTGS1APPTTRKDM4E | |
| Hispolon SCHEMBL15917285 | 0.85 | IAPP (0.74) | IAPPPTGS1APPTTRKDM4E | |
| Hispolon SCHEMBL17414113 | 0.85 | IAPP (0.74) | IAPPPTGS1APPTTRKDM4E | |
| Hispolon SCHEMBL30875919 | 0.85 | IAPP (0.74) | IAPPPTGS1APPTTRKDM4E | |
| SCHEMBL12220501 | 0.85 | IAPP (0.73) | IAPPPTGS1APPTTRKDM4E | |
| SCHEMBL21986902 | 0.85 | IAPP (0.73) | IAPPPTGS1APPTTRKDM4E | |
| SCHEMBL21986720 | 0.85 | IAPP (0.73) | IAPPPTGS1APPTTRKDM4E | |
| SCHEMBL2221673 | 0.83 | KDM4E (0.74) | IAPPPTGS1APPTTRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107441078-B | A kind of pharmaceutical composition and its preparation method and application for treating diabetes | 中南民族大学 | 2018-10-26 | — | — | CN | claimed |
| CN-107441078-A | A kind of pharmaceutical composition for treating diabetes and its production and use | 中南民族大学 | 2017-12-08 | — | — | CN | claimed |
| JP-4202127-A | — | — | None | — | — | JP | disclosed |
| US-20250327100-A1 | Strain of Pseudomonas Putida Genetically Modified to Express a Benzalacetone Reductase | BGENE GENETICS (FR) | 2025-10-23 | — | — | US | disclosed |
| CN-120284927-A | Application of 3, 4-dihydroxybenzylidene acetone in preparation of medicine for relieving intestinal injury of Leizhou black ducks | 广东海洋大学 | 2025-07-11 | — | — | CN | disclosed |
| CN-120284927-A | Application of 3, 4-dihydroxybenzylidene acetone in preparation of medicine for relieving intestinal injury of Leizhou black ducks | 广东海洋大学 | 2025-07-11 | — | — | CN | disclosed |
| CN-119818462-A | Chinese medicinal composition containing Osmunda japonica ketone and application thereof in preparing medicament for preventing and treating diabetic complications | 北京中医药大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-119818461-A | Traditional Chinese medicine composition and application thereof in preparation of medicines for treating diseases related to abnormal proliferation of epithelial cells | 北京中医药大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-119345166-A | Application of Osmunotone in promotion of collagen and/or elastin production | 上海家化联合股份有限公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-119345165-A | Anti-glycation application of osmunda japonica ketone | 上海家化联合股份有限公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-119345164-A | Anti-inflammatory and soothing effects of Osmunotone and application thereof | 上海家化联合股份有限公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-100346776-C | Remedies | TAKARA BIO INC (JP) | 2007-11-07 | — | — | CN | disclosed |
| US-7268160-B2 | Remedies | TAKARA BIO, INC. (JP) | 2007-09-11 | — | — | US | disclosed |
| EP-1666440-A1 | METHOD FOR PRODUCING AROMATIC UNSATURATED COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2006-06-07 | — | — | EP | disclosed |
| US-6689767-B2 | TRITERPENE BACTERICIDES | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2004-02-10 | — | — | US | disclosed |
| US-6689767-B2 | TRITERPENE BACTERICIDES | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2004-02-10 | — | — | US | disclosed |
| US-20030144316-A1 | Remedies | TAKARA BIO INC. (JP) | 2003-07-31 | — | — | US | disclosed |
| CN-1419448-A | Remedies | TAKARA BIO INC (JP) | 2003-05-21 | — | — | CN | disclosed |
| EP-1254658-A1 | REMEDIES | TAKARA BIO INC. (JP) | 2002-11-06 | — | — | EP | disclosed |
| JP-H04202127-A | INTERLEUKIN-1 PRODUCTION-INHIBITING AGENT | TERUMO CORP | 1992-07-22 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144316-A1 | Remedies | NGF, BDNF, NTRK2 | IAPP 42/4885PTGS1 200/4885APP 569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.