Sugi Predict

Sugi Predict / Compounds / SCHEMBL1881133

SCHEMBL1881133

SCHEMBL1881133

CC(=O)/C=C/c1ccc(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ IAPP P10997 4/20 1.00
▸ PTGS1 P23219 1/20 1.00
▸ APP P05067 3/20 0.69
▸ TTR P02766 3/20 0.69
▸ KDM4E B2RXH2 2/20 0.69
▸ HSD17B10 Q99714 2/20 0.69
▸ MAPT P10636 2/20 0.69
▸ PTPN1 P18031 2/20 0.69
▸ DPP4 P27487 2/20 0.69
▸ MEN1 O00255 1/20 0.69
▸ HDAC3 O15379 1/20 0.69
▸ CA12 O43570 1/20 0.69
▸ AKR1B10 O60218 1/20 0.69
▸ ALDH1A1 P00352 1/20 0.69
▸ CA1 P00915 1/20 0.69
▸ CA2 P00918 1/20 0.69
▸ LMNA P02545 1/20 0.69
▸ MMP1 P03956 1/20 0.69
▸ GLA P06280 1/20 0.69
▸ POLB P06746 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29364807 1.00 IAPP (1.00) IAPPPTGS1APPTTRKDM4E
SCHEMBL1881134 1.00 IAPP (1.00) IAPPPTGS1APPTTRKDM4E
Hispolon SCHEMBL15917284 0.85 IAPP (0.74) IAPPPTGS1APPTTRKDM4E
Hispolon SCHEMBL15917285 0.85 IAPP (0.74) IAPPPTGS1APPTTRKDM4E
Hispolon SCHEMBL17414113 0.85 IAPP (0.74) IAPPPTGS1APPTTRKDM4E
Hispolon SCHEMBL30875919 0.85 IAPP (0.74) IAPPPTGS1APPTTRKDM4E
SCHEMBL12220501 0.85 IAPP (0.73) IAPPPTGS1APPTTRKDM4E
SCHEMBL21986902 0.85 IAPP (0.73) IAPPPTGS1APPTTRKDM4E
SCHEMBL21986720 0.85 IAPP (0.73) IAPPPTGS1APPTTRKDM4E
SCHEMBL2221673 0.83 KDM4E (0.74) IAPPPTGS1APPTTRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4202127-A — — None — — JP disclosed
US-20250327100-A1 Strain of Pseudomonas Putida Genetically Modified to Express a Benzalacetone Reductase BGENE GENETICS (FR) 2025-10-23 — — US disclosed
WO-2024151693-A1 A VIBRANT AND STABLE BLUE COLORANT AND METHODS OF MAKING AND USE THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2024-07-18 — — WO disclosed
US-11872236-B2 Pharmacological agents for treating ocular diseases CALASIA PHARMACEUTICALS, INC. (US) 2024-01-16 — — US disclosed
US-11872236-B2 Pharmacological agents for treating ocular diseases CALASIA PHARMACEUTICALS, INC. (US) 2024-01-16 — — US disclosed
US-20230380460-A1 COLOURING COMPOSITION FOR FOOD PRODUCTS GIVAUDAN SA (CH) 2023-11-30 — — US disclosed
US-20230310299-A1 STABLE COMPOSITION COMPRISING POLYDATIN L'OREAL (FR) 2023-10-05 — — US disclosed
US-20230310299-A1 STABLE COMPOSITION COMPRISING POLYDATIN L'OREAL (FR) 2023-10-05 — — US disclosed
EP-3321259-B1 NEW PYRAZINE DERIVATIVE, AND PREPARATION METHOD AND MEDICAL APPLICATION THEREOF GUANGZHOU MAGPIE PHARMACEUTICAL CO LTD (CN) 2023-10-04 — — EP disclosed
US-11746364-B2 Enzymatic synthesis of kavalactones and flavokavains WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2023-09-05 — — US disclosed
US-7268160-B2 Remedies TAKARA BIO, INC. (JP) 2007-09-11 — — US disclosed
US-7268160-B2 Remedies TAKARA BIO, INC. (JP) 2007-09-11 — — US disclosed
US-20070015262-A1 Extracts from Ajuga reptans cell lines, their preparation and use I.R.B. ISTITUTO DI RICERCHE BIOTECNOLOGICHE S.R.L. (IT) 2007-01-18 — — US disclosed
US-20070015262-A1 Extracts from Ajuga reptans cell lines, their preparation and use I.R.B. ISTITUTO DI RICERCHE BIOTECNOLOGICHE S.R.L. (IT) 2007-01-18 — — US disclosed
US-20070004011-A1 Extracts obtained from cell line cultures from plants belonging to the Oleaceae family (e.g. Syringa vulgaris), their preparation and use I.R.B. ISTITUTO DI RICERCHE BIOTECNOLOGICHE S.R.I. (IT) 2007-01-04 — — US disclosed
US-20070004011-A1 Extracts obtained from cell line cultures from plants belonging to the Oleaceae family (e.g. Syringa vulgaris), their preparation and use I.R.B. ISTITUTO DI RICERCHE BIOTECNOLOGICHE S.R.I. (IT) 2007-01-04 — — US disclosed
EP-1666440-A1 METHOD FOR PRODUCING AROMATIC UNSATURATED COMPOUND Sumitomo Chemical Company, Limited (JP) 2006-06-07 — — EP disclosed
US-20030144316-A1 Remedies TAKARA BIO INC. (JP) 2003-07-31 — — US disclosed
EP-1254658-A1 REMEDIES TAKARA BIO INC. (JP) 2002-11-06 — — EP disclosed
JP-H04202127-A INTERLEUKIN-1 PRODUCTION-INHIBITING AGENT TERUMO CORP 1992-07-22 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230310299-A1 STABLE COMPOSITION COMPRISING POLYDATIN CTRB1, CCNB3, CTRB2 IAPP 2100/4885PTGS1 2833/4885APP 2613/4885
US-20070015262-A1 Extracts from Ajuga reptans cell lines, their preparation and use TTPA, FABP4, ACOX3 IAPP 2590/4885PTGS1 345/4885APP 2275/4885
US-20070004011-A1 Extracts obtained from cell line cultures from plants belonging to the Oleaceae family (e.g. Syringa vulgaris), their preparation and use CAT, CUTA, VAPA IAPP 2810/4885PTGS1 807/4885APP 3303/4885
US-11872236-B2 Pharmacological agents for treating ocular diseases CRYAA, CRYAB, TTR IAPP 97/4885PTGS1 218/4885APP 26/4885
US-20030144316-A1 Remedies NGF, BDNF, NTRK2 IAPP 42/4885PTGS1 200/4885APP 569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.