Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 3/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.73 |
| ▸ | BACE1 | P56817 | 2/20 | 0.64 |
| ▸ | APP | P05067 | 3/20 | 0.63 |
| ▸ | TTR | P02766 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | DPP4 | P27487 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15481424 | 0.87 | BACE1 (0.66) | IAPPPTGS1BACE1APPTTR | |
| SCHEMBL471934 | 0.85 | KDM4E (0.70) | IAPPPTGS1BACE1APPTTR | |
| SCHEMBL21986902 | 0.85 | IAPP (0.73) | IAPPPTGS1BACE1APPTTR | |
| SCHEMBL21986720 | 0.85 | IAPP (0.73) | IAPPPTGS1BACE1APPTTR | |
| SCHEMBL471935 | 0.85 | KDM4E (0.70) | IAPPPTGS1BACE1APPTTR | |
| SCHEMBL1881134 | 0.85 | IAPP (1.00) | IAPPPTGS1BACE1APPTTR | |
| SCHEMBL1881133 | 0.85 | IAPP (1.00) | IAPPPTGS1BACE1APPTTR | |
| SCHEMBL29364807 | 0.85 | IAPP (1.00) | IAPPPTGS1BACE1APPTTR | |
| SCHEMBL14926717 | 0.85 | IAPP (0.61) | IAPPPTGS1BACE1APPKDM4E | |
| SCHEMBL8965107 | 0.84 | BACE1 (0.88) | IAPPPTGS1BACE1APPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691947-B2 | Isoindoline compositions and methods for treating neurodegenerative disease | COGNITION THERAPEUTICS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
| US-20180086703-A1 | ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE | COGNITION THERAPEUTICS, INC. | 2018-03-29 | — | — | US | disclosed |
| US-20180002306-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING SWEET TASTE | CHROMOCELL CORP (US) | 2018-01-04 | — | — | US | disclosed |
| US-9796672-B2 | Isoindoline compositions and methods for treating neurodegenerative disease | COGNITION THERAPEUTICS, INC. (US) | 2017-10-24 | — | — | US | disclosed |
| US-20170144970-A1 | ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE | COGNITION THERAPEUTICS, INC. | 2017-05-25 | — | — | US | disclosed |
| EP-1567143-B1 | ANTHRANILIC ACID AMIDES AND THE DERIVATIVES THEREOF AS COSMETIC AND PHARMACEUTICAL AGENTS | SYMRISE AG (DE) | 2013-08-14 | — | — | EP | disclosed |
| US-8497361-B2 | Topoisomerase binding probe and method of use | SRI INTERNATIONAL (US) | 2013-07-30 | — | — | US | disclosed |
| US-20110256115-A1 | HYDROSOLUBLE [6)O-ALPHA-D-GLCP-(1->]N-6-O-BETA-D-GLCP-(1->-PHENOLIC DERIVATIVES WITH DERMOCOSMETIC, NUTRITIONAL AND THERAPEUTIC APPLICATIONS, AND COMPOSITIONS CONTAINING SAID WATER SOLUBLE COMPOUNDS | LIBRAGEN (FR) | 2011-10-20 | — | — | US | disclosed |
| WO-2008003978-A2 | DIOXO-ALKANES AND DIOXO-ALKENES | PHYTOPHARM PLC (GB) | 2008-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110256115-A1 | HYDROSOLUBLE [6)O-ALPHA-D-GLCP-(1->]N-6-O-BETA-D-GLCP-(1->-PHENOLIC DERIVATIVES WITH DERMOCOSMETIC, NUTRITIONAL AND THERAPEUTIC APPLICATIONS, AND COMPOSITIONS CONTAINING SAID WATER SOLUBLE COMPOUNDS | UGGT1, UGDH, CYP24A1 | IAPP 438/4885PTGS1 771/4885BACE1 645/4885 |
| US-11691947-B2 | Isoindoline compositions and methods for treating neurodegenerative disease | TMEM97, SLC18A2, PSD | IAPP 441/4885PTGS1 2452/4885BACE1 50/4885 |
| US-20180002306-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING SWEET TASTE | TAS2R10, TAS2R40, TAS2R5 | IAPP 41/4885PTGS1 2090/4885BACE1 4134/4885 |
| US-20180086703-A1 | ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE | TMEM97, SLC18A2, PSD | IAPP 441/4885PTGS1 2452/4885BACE1 50/4885 |
| US-20170144970-A1 | ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE | TMEM97, SLC18A2, PSD | IAPP 441/4885PTGS1 2452/4885BACE1 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.