Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.50 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10035355 | 0.84 | SMN1; SMN2 (0.55) | CYP19A1CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL21156862 | 0.83 | CYP19A1 (0.73) | CYP19A1CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL10338918 | 0.81 | CYP19A1 (0.76) | CYP19A1CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL2608833 | 0.81 | CHRNB2 (0.58) | — | |
| SCHEMBL14672093 | 0.81 | MAPT (0.57) | CYP3A4CYP2C9CYP2C19ALDH1A1NPC1 | |
| SCHEMBL20851318 | 0.80 | MAPT (0.58) | CYP3A4CYP2C9CYP2C19ALDH1A1NPC1 | |
| SCHEMBL16108295 | 0.79 | KMO (0.51) | CYP19A1CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL14129887 | 0.79 | CYP2D6 (1.00) | CYP19A1CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL31140254 | 0.77 | CYP2C9 (0.65) | CYP19A1CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL31140250 | 0.77 | CYP2C9 (0.65) | CYP19A1CYP3A4CYP2C9CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11794180-B2 | Tri-(adamantyl)phosphines and applications thereof | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2023-10-24 | — | — | US | disclosed |
| US-20230158480-A1 | TRI-(ADAMANTYL)PHOSPHINES AND APPLICATIONS THEREOF | UNIV PRINCETON (US) | 2023-05-25 | — | — | US | disclosed |
| WO-2017075581-A1 | TRI-(ADAMANTYL)PHOSPHINES AND APPLICATIONS THEREOF | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11794180-B2 | Tri-(adamantyl)phosphines and applications thereof | PADI3, ADA, ENTPD3 | CYP19A1 2835/4885CYP3A4 1515/4885CYP2C9 1260/4885 |
| US-20230158480-A1 | TRI-(ADAMANTYL)PHOSPHINES AND APPLICATIONS THEREOF | PADI3, ADA, ENTPD3 | CYP19A1 2835/4885CYP3A4 1515/4885CYP2C9 1260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.