SCHEMBL18813000

SCHEMBL18813000

C=C(C(=O)O)c1ccccc1Sc1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SIRT1 Q96EB6 1/20 0.62
▸ L3MBTL1 Q9Y468 4/20 0.45
▸ MAPT P10636 2/20 0.44
▸ TDP1 Q9NUW8 2/20 0.44
▸ POLB P06746 1/20 0.42
▸ ALDH1A1 P00352 4/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ BLM P54132 1/20 0.41
▸ LMNA P02545 2/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ HPGD P15428 3/20 0.41
▸ ATM Q13315 1/20 0.41
▸ NSD2 O96028 2/20 0.40
▸ KDM4E B2RXH2 2/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ GLA P06280 1/20 0.39
▸ SLC6A9 P48067 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8959187 0.80 SIRT1 (0.71) SIRT1L3MBTL1MAPTTDP1POLB
SCHEMBL231042 0.80 SIRT1 (0.71) SIRT1L3MBTL1MAPTTDP1POLB
SCHEMBL11123891 0.77 ALDH1A1 (0.52) MAPTPOLBALDH1A1SMN1; SMN2HPGD
SCHEMBL11476180 0.77 SIRT1 (0.67) SIRT1L3MBTL1MAPTTDP1POLB
SCHEMBL3075574 0.77 SIRT1 (0.67) SIRT1L3MBTL1MAPTTDP1POLB
SCHEMBL19187658 0.77 SIRT1 (0.56) SIRT1L3MBTL1MAPTTDP1POLB
SCHEMBL2417850 0.77 SIRT1 (0.67) SIRT1L3MBTL1MAPTTDP1POLB
SCHEMBL1030659 0.77 SIRT1 (1.00) SIRT1L3MBTL1MAPTTDP1POLB
SCHEMBL13518641 0.76 SIRT1 (0.61) SIRT1L3MBTL1MAPTTDP1POLB
SCHEMBL14744092 0.76 POLB (0.41) SIRT1MAPTPOLBALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3721292-A1 ADHESIVE-FREE PHOTOPOLYMER LAYER STRUCTURE Covestro Deutschland AG (DE) 2020-10-14 — — EP disclosed
EP-3374991-B1 KIT OF PARTS CONTAINING SEALING LAYER AND PHOTOPOLYMER COVESTRO DEUTSCHLAND AG (DE) 2019-10-23 — — EP disclosed
WO-2019110505-A1 ADHESIVE-FREE PHOTOPOLYMER LAYER STRUCTURE COVESTRO DEUTSCHLAND AG (DE) 2019-06-13 — — WO disclosed
EP-3495886-A1 GLUE-FREE PHOTOPOLYMER LAYER CONSTRUCTION Covestro Deutschland AG (DE) 2019-06-12 — — EP disclosed
EP-3166109-A1 KIT OF PARTS CONTAINING SEALING LAYER AND PHOTOPOLYMER Covestro Deutschland AG (DE) 2017-05-10 — — EP disclosed
Send feedback