Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.36 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9637880 | 0.83 | KDM4E (0.50) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL9408663 | 0.81 | KDM4E (0.47) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL250563 | 0.80 | ALDH1A1 (0.47) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27969998 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL851184 | 0.78 | KDM4E (0.44) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2841545 | 0.77 | ALDH1A1 (0.47) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL14764230 | 0.75 | KDM4E (0.60) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL3444493 | 0.75 | KDM4E (0.41) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28332710 | 0.75 | MEN1 (0.46) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| Styrene SCHEMBL11352647 | 0.74 | ALDH1A1 (0.41) | KDM4EALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105749868-A | Preparation of vinyl benzyl trimethyl ammonium chloride-modified carbon fibre adsorbent | 济南大学 | 2016-07-13 | — | — | CN | claimed |
| US-9873116-B2 | Ion exchange membrane, method for manufacturing same, module, and device | FUJIFILM CORPORATION (JP) | 2018-01-23 | — | — | US | disclosed |
| CN-105749868-B | A kind of preparation of vinylbenzyltrimethyl ammonium chloride PAN-ACF agent | 济南大学 | 2018-01-23 | — | — | CN | disclosed |
| CN-105749868-B | A kind of preparation of vinylbenzyltrimethyl ammonium chloride PAN-ACF agent | 济南大学 | 2018-01-23 | — | — | CN | disclosed |
| US-20170128931-A1 | ION EXCHANGE MEMBRANE, METHOD FOR MANUFACTURING SAME, MODULE, AND DEVICE | FUJIFILM CORPORATION (JP) | 2017-05-11 | — | — | US | disclosed |
| CN-105749868-A | Preparation of vinyl benzyl trimethyl ammonium chloride-modified carbon fibre adsorbent | 济南大学 | 2016-07-13 | — | — | CN | disclosed |