Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9408663 | 0.98 | KDM4E (0.47) | KDM4EALDH1A1TDP1TAAR1SLC6A2 | |
| Hydrochloric Acid SCHEMBL18816319 | 0.83 | KDM4E (0.52) | KDM4EALDH1A1TDP1TAAR1SLC6A2 | |
| Trifluoromethanesulfonic Acid SCHEMBL31031302 | 0.82 | GPR3 (0.35) | KDM4EALDH1A1TDP1 | |
| SCHEMBL9147273 | 0.80 | CYP3A4 (0.43) | KDM4EALDH1A1TDP1MAPK1CYP2D6 | |
| SCHEMBL31031308 | 0.80 | KDM4E (0.33) | KDM4EALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL250563 | 0.79 | ALDH1A1 (0.47) | KDM4EALDH1A1TDP1TAAR1SLC6A2 | |
| Hydrochloric Acid SCHEMBL2841545 | 0.79 | ALDH1A1 (0.47) | KDM4EALDH1A1TDP1TAAR1SLC6A2 | |
| Hydrochloric Acid SCHEMBL14764230 | 0.78 | KDM4E (0.60) | KDM4EALDH1A1TDP1TAAR1SLC6A2 | |
| Hydrochloric Acid SCHEMBL27969998 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1TDP1TAAR1SLC6A2 | |
| SCHEMBL851184 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1TDP1TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250355378-A1 | TONER AND METHOD OF MANUFACTURING TONER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2025-11-20 | — | — | US | disclosed |
| WO-2024162071-A1 | COMPOSITION, POLYMERIZABLE COMPOSITION, ION-EXCHANGE RESIN, ION-EXCHANGE MEMBRANE, MEMBRANE ELECTRODE ASSEMBLY, HYDROGEN PRODUCTION DEVICE, AND MANUFACTURING METHOD OF ION EXCHANGE MEMBRANE | 株式会社トクヤマ | 2024-08-08 | — | — | WO | disclosed |
| US-20200117107-A1 | POSITIVELY CHARGEABLE TONER, IMAGE FORMING APPARATUS, AND IMAGE FORMATION METHOD | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2020-04-16 | — | — | US | disclosed |
| US-10564559-B2 | Positively chargeable toner, image forming apparatus and image forming method | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2020-02-18 | — | — | US | disclosed |
| US-20190332026-A1 | POSITIVELY CHARGEABLE TONER, IMAGE FORMING APPARATUS AND IMAGE FORMING METHOD | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2019-10-31 | — | — | US | disclosed |
| EP-0497972-A1 | CHEMILUMINESCENT 3-(SUBSTITUTED ADAMANT-2'-YLIDENE) 1,2-DIOXETANES | TROPIX, INC. (US) | 1992-08-12 | — | — | EP | disclosed |
| WO-1992004341-A1 | CHEMILUMINESCENT 3-(SUBSTITUTED ADAMANT-2'-YLIDENE) 1,2-DIOXETANES | TROPIX, INC. (US) | 1992-03-19 | — | — | WO | disclosed |
| US-4454060-A | Liquid detergent composition with a cationic foam stabilizing copolymer containing pendant quaternary nitrogen groups and pendant hydrophobic groups | COLGATE-PALMOLIVE COMPANY (US) | 1984-06-12 | — | — | US | disclosed |