Hydrochloric Acid

Hydrochloric Acid

SCHEMBL2841545

C=CCC(C)[N+](C)(C)Cc1ccccc1.[Cl-]

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 known ✓ P23975 2/20 0.37
SLC6A3 known ✓ Q01959 1/20 0.37
ALDH1A1 P00352 2/20 0.47
KDM4E B2RXH2 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.39
KMT2A Q03164 3/20 0.38
TAAR1 Q96RJ0 2/20 0.37
MAOA P21397 1/20 0.37
SLC6A4 P31645 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
CYP2A6 P11509 1/20 0.37
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
MEN1 O00255 2/20 0.37
TP53 P04637 1/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 2/20 0.36
CYP2C19 P33261 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27969998 0.81 KDM4E (0.46) ALDH1A1KDM4ETDP1SMN1; SMN2KMT2A
Hydrochloric Acid SCHEMBL16714236 0.80 ALDH1A1 (0.44) ALDH1A1KDM4ETDP1SMN1; SMN2KMT2A
Hydrochloric Acid SCHEMBL9637880 0.79 KDM4E (0.50) ALDH1A1KDM4ETDP1SMN1; SMN2KMT2A
SCHEMBL6530596 0.78 SMN1; SMN2 (0.45) ALDH1A1KDM4ETDP1SMN1; SMN2KMT2A
Hydrochloric Acid SCHEMBL18816319 0.77 KDM4E (0.52) ALDH1A1KDM4ETDP1SMN1; SMN2KMT2A
SCHEMBL9408663 0.77 KDM4E (0.47) ALDH1A1KDM4ETDP1SMN1; SMN2KMT2A
Hydrochloric Acid SCHEMBL14764230 0.75 KDM4E (0.60) ALDH1A1KDM4ETDP1SMN1; SMN2KMT2A
Hydrochloric Acid SCHEMBL15967972 0.74 TSHR (0.46) ALDH1A1KDM4ETDP1KMT2AMEN1
SCHEMBL5944539 0.73 KDM4E (0.56) ALDH1A1KDM4ETDP1SMN1; SMN2KMT2A
SCHEMBL7649116 0.73 KDM4E (0.47) ALDH1A1KDM4ETDP1SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2207416-B1 ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM IMERYS FILTRATION MINERALS INC (US) 2018-11-07 EP disclosed
US-20100239679-A1 ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM WORLD MINERALS, INC. (US) 2010-09-23 US disclosed
EP-2207416-A1 ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM World Minerals, Inc. (US) 2010-07-21 EP disclosed
WO-2009045941-A1 ENHANCED RETENTION CAPABILITIES THROUGH METHODS COMPRISING SURFACE TREATMENT OF FUNCTIONAL PARTICULATE CARRIER MATERIALS, AND FUNCTIONAL PARTICULATE CARRIER MATERIALS MADE THEREFROM WORLD MINERALS, INC. (US) 2009-04-09 WO disclosed
US-5114483-A Open-graded asphalt CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1992-05-19 US disclosed
US-4762565-A Open-graded asphalt CHEVRON RESEARCH COMPANY (US) 1988-08-09 US disclosed
WO-1988003157-A1 OPEN-GRADED ASPHALT CHEVRON RESEARCH COMPANY (US) 1988-05-05 WO disclosed
US-4333862-A Detergent compositions comprising mixture of cationic, anionic and nonionic surfactants THE PROCTER & GAMBLE COMPANY (US) 1982-06-08 US disclosed
EP-0051986-A2 Detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-05-19 EP disclosed
US-4321165-A Detergent compositions comprising cationic, anionic and nonionic surfactants THE PROCTER & GAMBLE COMPANY (US) 1982-03-23 US disclosed
EP-0000225-A1 Solid detergent composition for improved greasy soil removal THE PROCTER & GAMBLE COMPANY (US) 1979-01-10 EP disclosed
EP-0000224-A1 Liquid detergent composition for improved greasy soil removal THE PROCTER & GAMBLE COMPANY (US) 1979-01-10 EP disclosed