SCHEMBL1881870

SCHEMBL1881870

CCCCc1cc(CCC)c(CCC)c(-c2cccc(OPOc3cccc(-c4cc(CCCC)cc(CCC)c4CCC)c3-c3cc(CCCC)cc(CCC)c3CCC)c2-c2cc(CCCC)cc(CCC)c2CCC)c1

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.32
CTSG P08311 1/20 0.32
LPL P06858 1/20 0.32
LIPG Q9Y5X9 1/20 0.32
NPC1 O15118 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
PSMB5 P28074 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1881872 0.91 ELANE (0.33) ELANECTSGLPLLIPGNPC1
SCHEMBL2693763 0.77 NPC1 (0.34) ELANECTSGLPLLIPGNPC1
SCHEMBL1887035 0.70 GPR3 (0.43) LPLLIPG
SCHEMBL1881742 0.69 PTGS2 (0.43) ELANECTSGLIPG
SCHEMBL6745910 0.68 LTB4R (0.41) ELANEHPGD
SCHEMBL1880864 0.67 TLR8 (0.42) LPLLIPG
SCHEMBL1890044 0.67 ELANE (0.41) ELANECTSG
SCHEMBL11341961 0.67 GPR3 (0.39) ELANECTSGNPC1MAPK1HTT
SCHEMBL1995983 0.67 PSMB5 (0.42) ELANECTSGNPC1MAPK1HTT
SCHEMBL6742752 0.66 PTGS2 (0.45) ELANECTSGLIPGHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947342-B2 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-24 US disclosed
EP-2012150-A1 POLARIZING PLATE PROTECTION FILM, METHOD FOR PRODUCING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY Konica Minolta Opto, Inc. (JP) 2009-01-07 EP disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed