Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18819093 | 0.79 | BRD4 (0.32) | — | |
| SCHEMBL15075698 | 0.79 | EPHX2 (0.39) | EPHX2GFER | |
| SCHEMBL18819656 | 0.78 | EPHX2 (0.35) | EPHX2MEN1KMT2ASMN1; SMN2GFER | |
| SCHEMBL15075645 | 0.75 | ALDH1A1 (0.39) | EPHX2ALDH1A1SMN1; SMN2GFER | |
| SCHEMBL15075715 | 0.74 | EPHX2 (0.35) | EPHX2GFER | |
| SCHEMBL18819443 | 0.74 | EPHX2 (0.41) | EPHX2ALDH1A1CYP3A4YTHDF2GFER | |
| SCHEMBL18819722 | 0.69 | EPHX2 (0.37) | EPHX2MEN1ALDH1A1KMT2AGFER | |
| SCHEMBL18819571 | 0.67 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL18819560 | 0.67 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL19246030 | 0.64 | LMNA (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017071606-A1 | MEDICAL USE OF HYDROXYL PURINE COMPOUND | 南京明德新药研发股份有限公司 | 2017-05-04 | — | — | WO | disclosed |