Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18819443 | 0.79 | EPHX2 (0.41) | EPHX2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL15075698 | 0.71 | EPHX2 (0.39) | EPHX2GFER | |
| SCHEMBL15075715 | 0.70 | EPHX2 (0.35) | EPHX2GFER | |
| SCHEMBL18819656 | 0.70 | EPHX2 (0.35) | EPHX2MEN1KMT2AGFER | |
| SCHEMBL18819094 | 0.69 | EPHX2 (0.34) | EPHX2ALDH1A1MEN1KMT2AGFER | |
| SCHEMBL15075645 | 0.68 | ALDH1A1 (0.39) | EPHX2ALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL12299909 | 0.65 | — | — | |
| SCHEMBL19987789 | 0.62 | EPHX2 (0.30) | EPHX2 | |
| SCHEMBL18819567 | 0.62 | EPHX2 (0.35) | EPHX2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL17791200 | 0.61 | MAPT (0.33) | ALDH1A1MAPTMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017071606-A1 | MEDICAL USE OF HYDROXYL PURINE COMPOUND | 南京明德新药研发股份有限公司 | 2017-05-04 | — | — | WO | disclosed |