Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRD2 | P25440 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18819722 | 0.79 | EPHX2 (0.37) | EPHX2GFERDAOALDH1A1KDM4E | |
| SCHEMBL15075698 | 0.76 | EPHX2 (0.39) | EPHX2GFERKDM1A | |
| SCHEMBL18819656 | 0.75 | EPHX2 (0.35) | EPHX2GFER | |
| SCHEMBL18819094 | 0.74 | EPHX2 (0.34) | EPHX2GFERCYP3A4ALDH1A1YTHDF2 | |
| SCHEMBL15075645 | 0.73 | ALDH1A1 (0.39) | EPHX2GFERALDH1A1HPGDALOX15 | |
| SCHEMBL15075715 | 0.72 | EPHX2 (0.35) | EPHX2GFER | |
| SCHEMBL18819567 | 0.67 | EPHX2 (0.35) | EPHX2GFERDAOCYP3A4MAPK1 | |
| SCHEMBL29148112 | 0.67 | EPHX2 (0.42) | EPHX2GFERDAOCYP3A4MAPK1 | |
| SCHEMBL11294427 | 0.66 | EPHX2 (0.38) | EPHX2GFERDAOCYP3A4MAPK1 | |
| SCHEMBL19987948 | 0.65 | EPHX2 (0.41) | EPHX2GFERDAOCYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019171397-A1 | SYNERGISTIC HERBAL COMPOSITIONS FOR THE TREATMENT OF OBESITY AND OVERWEIGHT | LAILA NUTRACEUTICALS (IN) | 2019-09-12 | — | — | WO | disclosed |
| WO-2017071606-A1 | MEDICAL USE OF HYDROXYL PURINE COMPOUND | 南京明德新药研发股份有限公司 | 2017-05-04 | — | — | WO | disclosed |