Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28101189 | 0.98 | ATM (0.52) | ATMGPR84MEN1CYP3A4KMT2A | |
| Hydrochloric Acid SCHEMBL28905061 | 0.98 | ATM (0.52) | ATMGPR84MEN1CYP3A4KMT2A | |
| SCHEMBL1959661 | 0.91 | ATM (0.47) | ATMGPR84MEN1CYP3A4KMT2A | |
| SCHEMBL1202543 | 0.74 | IMPDH2 (0.63) | ATMGPR84MEN1CYP3A4KMT2A | |
| SCHEMBL28907736 | 0.73 | ATM (0.52) | ATMGPR84MEN1CYP3A4KMT2A | |
| SCHEMBL2012509 | 0.72 | ATM (0.56) | ATMGPR84MEN1CYP3A4KMT2A | |
| SCHEMBL2953261 | 0.72 | ATM (0.56) | ATMGPR84MEN1CYP3A4KMT2A | |
| SCHEMBL17232879 | 0.71 | GPR84 (0.62) | ATMGPR84MEN1CYP3A4KMT2A | |
| SCHEMBL555325 | 0.71 | PARP1 (0.55) | ATMMEN1CYP3A4KMT2AMAPT | |
| SCHEMBL1959665 | 0.70 | ATM (0.77) | ATMGPR84MEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4994 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148272-A1 | AZA BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS | RIBOSCIENCE LLC (US) | 2024-07-11 | — | — | WO | claimed |
| US-20240218022-A1 | ANTI-VISTA MACROCYCLIC PEPTIDES AND COMPOSITIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-07-04 | — | — | US | claimed |
| US-20240209005-A1 | BICYCLIC HETEROARYL BORONATE DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS | RIBOSCIENCE LLC | 2024-06-27 | — | — | US | claimed |
| US-20240199661-A1 | BICYCLIC HETEROARYL PHOSPHONATE DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS | RIBOSCIENCE LLC | 2024-06-20 | — | — | US | claimed |
| US-20240197666-A1 | DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) | K-GEN THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | US | claimed |
| US-12011454-B2 | Nicotinamide mononucleotide derivatives and use thereof in the treatment and prevention of a red blood cell disorder | NUVAMID SA (CH) | 2024-06-18 | — | — | US | claimed |
| EP-4380577-A1 | NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES FOR USE IN THE TREATMENT OF SAPHO SYNDROME | Nuvamid SA (CH) | 2024-06-12 | — | — | EP | claimed |
| CN-118165073-A | FAP inhibitor and preparation method and application thereof | 中国药科大学 | 2024-06-11 | — | — | CN | claimed |
| CN-118055943-A | Cyclic peptide antibiotics | 基因泰克公司 | 2024-05-17 | — | — | CN | claimed |
| CN-117946067-A | Method for realizing deuteration methylation of nucleophile | 南京工业大学 | 2024-04-30 | — | — | CN | claimed |
| US-4192882-A | SUBSTITUTED INDOLES FOR RELIEVING ANGIOTENSIN RELATED HYPERTENSION | E. R. SQUIBB & SONS, INC. (US) | 1980-03-11 | — | — | US | claimed |
| EP-0007477-A1 | 1-(3-Mercapto-2-methylpropanoyl)prolyl amino acid derivatives and salts thereof, processes for their preparation, and pharmaceutical compositions containing such compounds | Dainippon Pharmaceutical Co., Ltd. (JP) | 1980-02-06 | — | — | EP | claimed |
| US-4154736-A | Indolylalkylene amino acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | claimed |
| US-4140786-A | ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-02-20 | — | — | US | claimed |
| US-4123607-A | BACTERICIDES | AMERICAN CYANAMID COMPANY (US) | 1978-10-31 | — | — | US | claimed |
| US-4104371-A | Psychopharmacologically active peptides and peptide-derivatives, and the use thereof | AKZONA INCORPORATED (US) | 1978-08-01 | — | — | US | claimed |
| US-4072698-A | OPTICALLY ACTIVE ACIDS WITH KETONE OR ALDEHYDE CATALYST | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | claimed |
| US-4066661-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED TRICHLOROACETAMIDINE DERIVATIVES | MERCK & CO., INC. (US) | 1978-01-03 | — | — | US | claimed |
| US-4065465-A | Process for the preparation of substituted trichloroacetamidine derivatives | MERCK & CO., INC. (US) | 1977-12-27 | — | — | US | claimed |
| US-4065464-A | Process for the preparation of substituted trichloroacetamidine derivatives | MERCK & CO., INC. (US) | 1977-12-27 | — | — | US | claimed |