Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 8/20 | 0.44 |
| ▸ | PYGL | P06737 | 3/20 | 0.42 |
| ▸ | PYGM | P11217 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20888681 | 1.00 | PYGB (0.44) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL20888684 | 1.00 | PYGB (0.44) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL18805897 | 1.00 | PYGB (0.44) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL14432962 | 1.00 | PYGB (0.44) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL18819607 | 0.94 | PYGB (0.39) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL18819604 | 0.94 | PYGB (0.39) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL9221248 | 0.84 | PYGB (0.47) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL29048829 | 0.79 | PYGB (0.45) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL9862851 | 0.77 | PYGB (0.45) | PYGBPYGLPYGMLMNAGBA1 | |
| SCHEMBL1842511 | 0.77 | PYGB (0.45) | PYGBPYGLPYGMLMNAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10683327-B2 | Compounds, linker-drugs and ligand-drug conjugates | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2020-06-16 | — | — | US | disclosed |
| US-10618935-B2 | Antibody-drug conjugate (ADC) and method for forming the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2020-04-14 | — | — | US | disclosed |
| US-10233212-B2 | Compounds, linker-drugs and ligand-drug conjugates | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2019-03-19 | — | — | US | disclosed |
| US-20180016300-A1 | COMPOUNDS, LINKER-DRUGS AND LIGAND-DRUG CONJUGATES | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2018-01-18 | — | — | US | disclosed |
| US-20170119902-A1 | ANTIBODY-DRUG CONJUGATE (ADC) AND METHOD FOR FORMING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180016300-A1 | COMPOUNDS, LINKER-DRUGS AND LIGAND-DRUG CONJUGATES | SLC43A1, HCAR3, SLC7A1 | PYGB 4581/4885PYGL 3283/4885PYGM 4812/4885 |
| US-10683327-B2 | Compounds, linker-drugs and ligand-drug conjugates | SLC43A1, HCAR3, SLC7A1 | PYGB 4581/4885PYGL 3283/4885PYGM 4812/4885 |
| US-10233212-B2 | Compounds, linker-drugs and ligand-drug conjugates | SLC43A1, HCAR3, SLC7A1 | PYGB 4581/4885PYGL 3283/4885PYGM 4812/4885 |
| US-20170119902-A1 | ANTIBODY-DRUG CONJUGATE (ADC) AND METHOD FOR FORMING THE SAME | DNPEP, DLST, DDOST | PYGB 2867/4885PYGL 2673/4885PYGM 3805/4885 |
| US-10618935-B2 | Antibody-drug conjugate (ADC) and method for forming the same | DNPEP, DLST, DDOST | PYGB 2867/4885PYGL 2673/4885PYGM 3805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.