Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | PRKDC | P78527 | 4/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.34 |
| ▸ | CDC14B | O60729 | 2/20 | 0.33 |
| ▸ | CDC14A | Q9UNH5 | 2/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18820384 | 0.89 | ALOX5 (0.53) | ALOX5PRKDCGGPS1CRHBPCRHR2 | |
| SCHEMBL18820364 | 0.87 | ALOX5 (0.51) | ALOX5PRKDCGGPS1CRHBPCRHR2 | |
| SCHEMBL18820363 | 0.87 | ALOX5 (0.51) | ALOX5PRKDCGGPS1CRHBPCRHR2 | |
| SCHEMBL20762353 | 0.87 | ALOX5 (0.44) | ALOX5PRKDCGGPS1PTGES2 | |
| SCHEMBL18820519 | 0.87 | L3MBTL1 (0.45) | ALOX5PRKDCGGPS1CRHBPCRHR2 | |
| SCHEMBL18820371 | 0.86 | ALOX5 (0.57) | ALOX5PRKDCGGPS1CRHBPCRHR2 | |
| SCHEMBL18820368 | 0.85 | ALOX5 (0.56) | ALOX5PRKDCGGPS1CRHBPCRHR2 | |
| SCHEMBL18820568 | 0.85 | ALOX5 (0.49) | ALOX5PRKDCGGPS1CRHBPCRHR2 | |
| SCHEMBL18820356 | 0.84 | CRHBP (0.38) | ALOX5PRKDCCRHBPCRHR2KEAP1 | |
| SCHEMBL18820359 | 0.84 | PLA2G2A (0.39) | ALOX5CRHBPCRHR2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017071791-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-05-04 | — | — | WO | disclosed |