⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21414336 | 0.80 | DRD2 (0.33) | — | |
| SCHEMBL19498162 | 0.77 | CYP1A2 (0.32) | — | |
| SCHEMBL16639804 | 0.75 | DRD2 (0.34) | — | |
| SCHEMBL19498567 | 0.75 | ABHD6 (0.43) | — | |
| SCHEMBL19498186 | 0.72 | NCF1 (0.38) | — | |
| SCHEMBL19498187 | 0.72 | DRD2 (0.37) | — | |
| SCHEMBL23103392 | 0.71 | MAOA (0.43) | — | |
| SCHEMBL20203638 | 0.71 | CYP2C9 (0.44) | — | |
| SCHEMBL21414393 | 0.71 | PDCD1 (0.35) | — | |
| SCHEMBL20203493 | 0.70 | MAPT (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828373-B2 | 2-amino-pyrido[2,3-D]pyrimidin-7(8H)-one derivatives as CDK inhibitors and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-11-28 | — | — | US | disclosed |
| US-20170121323-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE DERIVATIVES AS CDK INHIBITORS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-05-04 | — | — | US | disclosed |