Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 4/20 | 0.45 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GALK1 | P51570 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24735024 | 0.94 | PLA2G2A (0.45) | PLA2G2APLA2G4APLA2G10PRKDCMAPT | |
| SCHEMBL12037309 | 0.93 | PGR (0.42) | PLA2G2APLA2G4APLA2G10PRKDCMAPT | |
| SCHEMBL4567321 | 0.92 | CRHBP (0.43) | PLA2G2APLA2G4APLA2G10MAPTL3MBTL1 | |
| SCHEMBL12037307 | 0.92 | PGR (0.41) | PLA2G2APLA2G4APLA2G10PRKDCMAPT | |
| SCHEMBL17692268 | 0.92 | PLA2G2A (0.43) | PLA2G2APLA2G4APLA2G10PRKDCMAPT | |
| SCHEMBL22876610 | 0.91 | PLA2G2A (0.41) | PLA2G2APLA2G4APLA2G10PRKDCMAPT | |
| SCHEMBL18820491 | 0.90 | PLA2G2A (0.47) | PLA2G2APLA2G4APLA2G10PRKDCMAPT | |
| SCHEMBL18820357 | 0.90 | CRHBP (0.39) | PLA2G2APLA2G4APLA2G10MAPTL3MBTL1 | |
| SCHEMBL17692257 | 0.90 | ALDH1A1 (0.44) | PLA2G2APLA2G4APLA2G10MAPTL3MBTL1 | |
| SCHEMBL1636525 | 0.89 | CRHBP (0.41) | PLA2G2APLA2G4APLA2G10MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11355714-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2022-06-07 | — | — | US | disclosed |
| US-20190058133-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-02-21 | — | — | US | disclosed |
| WO-2017071791-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11355714-B2 | Materials for organic electroluminescent devices | SLCO4C1, SLCO2A1, SLCO2B1 | PLA2G2A 3762/4885PLA2G4A 4439/4885PLA2G10 4026/4885 |
| US-20190058133-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | SLCO4C1, SLCO2A1, SLCO2B1 | PLA2G2A 3762/4885PLA2G4A 4439/4885PLA2G10 4026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.