SCHEMBL18820587

SCHEMBL18820587

CC1(C)OB(c2ccc3oc4c(-c5ccc6c(c5)-c5cccc7cccc-6c57)cccc4c3c2)OC1(C)C

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 9/20 0.39
LPL P06858 8/20 0.39
ALOX5 P09917 2/20 0.38
CSF1R P07333 1/20 0.33
EGFR P00533 1/20 0.32
PRMT5 O14744 1/20 0.32
WDR77 Q9BQA1 1/20 0.32
IRAK4 Q9NWZ3 1/20 0.30
PRKDC P78527 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30
GGPS1 O95749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25729691 0.84 CSF1R (0.37) LIPGLPLCSF1REGFRPRMT5
SCHEMBL22737993 0.84 ALOX5 (0.50) LIPGLPLALOX5CSF1REGFR
SCHEMBL24119079 0.82 LIPG (0.49) LIPGLPLALOX5CSF1REGFR
SCHEMBL24217342 0.80 ALOX5 (0.48) LIPGLPLALOX5CSF1REGFR
SCHEMBL25223314 0.79 LIPG (0.61) LIPGLPLCA1CA2CA9
SCHEMBL2229145 0.79 LIPG (0.48) LIPGLPLPRMT5WDR77IRAK4
SCHEMBL22112754 0.79 PRKDC (0.40) LIPGLPLALOX5CSF1REGFR
SCHEMBL18820572 0.79 ALOX5 (0.48) ALOX5PRKDCGGPS1
SCHEMBL25673146 0.78 LPL (0.40) LIPGLPLCSF1REGFRPRMT5
SCHEMBL24654439 0.78 LIPG (0.49) LIPGLPLIRAK4CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3368520-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-04-26 EP disclosed
US-11355714-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2022-06-07 US disclosed
US-20190058133-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-02-21 US disclosed
WO-2017071791-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-05-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11355714-B2 Materials for organic electroluminescent devices SLCO4C1, SLCO2A1, SLCO2B1 LIPG 2734/4885LPL 4054/4885ALOX5 1495/4885
US-20190058133-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2A1, SLCO2B1 LIPG 2734/4885LPL 4054/4885ALOX5 1495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.