SCHEMBL1882142

SCHEMBL1882142

CC(C)(C)c1ccccc1-c1cccc(OPOc2cccc(-c3ccccc3C(C)(C)C)c2-c2ccccc2C(C)(C)C)c1-c1ccccc1C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.35
CA2 P00918 1/20 0.34
ALDH1A1 P00352 6/20 0.33
TDP1 Q9NUW8 2/20 0.33
TSHR P16473 1/20 0.33
TRPA1 O75762 1/20 0.33
ATM Q13315 1/20 0.33
PRKDC P78527 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAPT P10636 2/20 0.31
TP53 P04637 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
PTPN5 P54829 1/20 0.31
KDM4E B2RXH2 3/20 0.31
GAA P10253 2/20 0.31
RXRA P19793 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1882143 0.87 CA2 (0.36) BCHECA2ALDH1A1TDP1TSHR
SCHEMBL4437004 0.83 NPC1 (0.37) ALDH1A1
SCHEMBL1897892 0.83 TRPA1 (0.33) TRPA1PTPN5
SCHEMBL345317 0.81 PTPN5 (0.37) BCHECA2ALDH1A1TDP1TSHR
SCHEMBL690036 0.80 CA2 (0.34) BCHECA2ALDH1A1TDP1TSHR
SCHEMBL544837 0.78 BCHE (0.32) BCHECA2ALDH1A1TDP1TSHR
SCHEMBL29497967 0.78 INPPL1 (0.45) BCHECA2ALDH1A1TDP1ATM
SCHEMBL345318 0.78 INPPL1 (0.45) BCHECA2ALDH1A1TDP1ATM
SCHEMBL499990 0.78 NPC1 (0.39) ALDH1A1
SCHEMBL6904484 0.78 ALDH1A1 (0.37) CA2ALDH1A1TDP1TSHRATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8697788-B2 Polycarbonate resin composition and molded article thereof TEIJIN CHEMICALS, LTD. (JP) 2014-04-15 US disclosed
US-20120095141-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF TEIJIN CHEMICALS, LTD. (JP) 2012-04-19 US disclosed
US-7947342-B2 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-24 US disclosed
EP-2012150-A1 POLARIZING PLATE PROTECTION FILM, METHOD FOR PRODUCING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY Konica Minolta Opto, Inc. (JP) 2009-01-07 EP disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed