SCHEMBL499990

SCHEMBL499990

CC(C)(C)c1ccc(-c2cccc(-c3ccccc3OPOc3ccccc3-c3cccc(-c4ccc(C(C)(C)C)cc4C(C)(C)C)c3-c3ccc(C(C)(C)C)cc3C(C)(C)C)c2-c2ccc(C(C)(C)C)cc2C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
PLA2G1B P04054 1/20 0.39
NFKB1 P19838 1/20 0.39
CASP3 P42574 1/20 0.39
RAB9A P51151 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ATG4B Q9Y4P1 1/20 0.39
STK10 O94804 1/20 0.33
SLK Q9H2G2 1/20 0.33
APEX1 P27695 1/20 0.31
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30
MAPK14 Q16539 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4437004 0.92 NPC1 (0.37) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL29388693 0.84 ALDH1A1 (0.47) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL29496602 0.81 ALDH1A1 (0.36) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL3025383 0.81 ALDH1A1 (0.36) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL18063625 0.81 ALDH1A1 (0.42) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL4920238 0.81 ALDH1A1 (0.49) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL5080716 0.79 NPC1 (0.44) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL1930528 0.78 NPC1 (0.39) NPC1ALDH1A1PLA2G1BNFKB1CASP3
SCHEMBL1882142 0.78 BCHE (0.35) ALDH1A1
SCHEMBL10778906 0.78 NPC1 (0.42) NPC1ALDH1A1PLA2G1BNFKB1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260098152-A1 RESIN COMPOSITION AND MOLDED ARTICLE OF SAME TEIJIN LIMITED (JP) 2026-04-09 US disclosed
US-20260008920-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2026-01-08 US disclosed
EP-4667531-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Teijin Limited (JP) 2025-12-24 EP disclosed
EP-4596627-A1 RESIN COMPOSITION AND MOLDED ARTICLE OF SAME Teijin Limited (JP) 2025-08-06 EP disclosed
EP-4585644-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE FORMED OF SAME Teijin Limited (JP) 2025-07-16 EP disclosed
US-12351697-B2 Resin composition for infrared ray-blocking transparent member, and molded article TEIJIN LIMITED (JP) 2025-07-08 US disclosed
WO-2025105384-A1 RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING SAME 帝人株式会社 2025-05-22 WO disclosed
EP-3623427-B1 RESIN COMPOSITION AND MOLDED ARTICLE DAIKIN IND LTD (JP) 2024-05-22 EP disclosed
US-20240117184-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE TEIJIN LIMITED (JP) 2024-04-11 US disclosed
WO-2024070340-A1 RESIN COMPOSITION AND MOLDED ARTICLE OF SAME 帝人株式会社 2024-04-04 WO disclosed
EP-1624012-A1 SHEET-FORM WINDOW MEMBER AND WINDOW STRUCTURE Teijin Chemicals, Ltd. (JP) 2006-02-08 EP disclosed
EP-1553140-A1 POLYCARBONATE RESIN COMPOSITION, PELLET THEREOF, AND MOLDED ARTICLE THEREOF Teijin Chemicals, Ltd. (JP) 2005-07-13 EP disclosed
EP-1191065-B1 RECLAIMED RESIN COMPOSITION TEIJIN CHEMICALS LTD (JP) 2005-02-09 EP disclosed
US-20040152806-A1 Polycarbonate resin composition, pellets thereof and molded article thereof TEIJIN CHEMICALS LTD. (JP) 2004-08-05 US disclosed
US-20040138378-A1 Regenerated resin composition TEIJIN CHEMICALS LTD. (JP) 2004-07-15 US disclosed
US-6686041-B2 HIGHLY UNIFORM CONCENTRATION; NONSTREAKING; EXCELLENT INFORMATION WRITABILITY AND READABILITY TEIJIN CHEMICALS LTD (JP) 2004-02-03 US disclosed
US-20030124351-A1 HIGHLY UNIFORM CONCENTRATION; NONSTREAKING; EXCELLENT INFORMATION WRITABILITY AND READABILITY TEIJIN CHEMICALS LTD. (JP) 2003-07-03 US disclosed
US-20030065092-A1 Reclaimed resin composition TEIJIN CHEMICALS, LTD. (JP) 2003-04-03 US disclosed
EP-1236758-A1 COLORED MASTER PELLET FOR OPTICAL MOLDINGS AND COLORED OPTICAL DISK SUBSTRATE Teijin Chemicals, Ltd. (JP) 2002-09-04 EP disclosed
EP-1191065-A1 RECLAIMED RESIN COMPOSITION Teijin Chemicals, Ltd. (JP) 2002-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098152-A1 RESIN COMPOSITION AND MOLDED ARTICLE OF SAME CYC1, MT-CO2, SCO2 NPC1 3567/4885ALDH1A1 2030/4885PLA2G1B 1879/4885
US-20260008920-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF NOP2, CCT2, RPL8 NPC1 2405/4885ALDH1A1 1820/4885PLA2G1B 1793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.