SCHEMBL1882160

SCHEMBL1882160

Oc1ccc(C2=NCCN2)cc1

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 13/20 0.66
LMNA P02545 1/20 0.63
RECQL P46063 1/20 0.63
TOP2A P11388 2/20 0.61
TOP2B Q02880 2/20 0.61
HTR1D P28221 1/20 0.59
ADRA1A P35348 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5476725 0.89 NISCH (0.79) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL6055672 0.84 NISCH (0.49) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL6055796 0.84 NISCH (0.49) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL1685409 0.79 NISCH (0.66) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL8141372 0.79 NISCH (1.00) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL17826831 0.79 NISCH (0.66) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL1209074 0.79 NISCH (0.66) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL2518908 0.79 NISCH (0.66) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL771337 0.79 NISCH (0.66) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL1886692 0.79 NISCH (1.00) NISCHLMNARECQLTOP2ATOP2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110224335-A1 INK COMPOSITION AND METHOD OF FABRICATING LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME KIM SUNG-HEE 2011-09-15 US claimed
US-7935552-B2 Ink composition and method of fabricating liquid crystal display device using the same LG DISPLAY CO., LTD. (KR) 2011-05-03 US claimed
CN-101993632-A Ink composition DONGJIN SEMICHEM CO LTD 2011-03-30 CN claimed
CN-101735690-A Ink composition and method of fabricating liquid crystal display device using the same LG DISPLAY CO LTD 2010-06-16 CN claimed
US-20100120181-A1 INK COMPOSITION AND METHOD OF FABRICATING LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2010-05-13 US claimed
WO-2022139594-A1 AMIDES AND SOLVENT FREE METHOD FOR THEIR MANUFACTURE KLINGELBERG PRODUCTS AS (NO) 2022-06-30 WO disclosed
WO-2022139593-A1 AMIDINES AND SOLVENT FREE METHOD FOR THEIR MANUFACTURE KLINGELBERG PRODUCTS AS (NO) 2022-06-30 WO disclosed
WO-2022139222-A1 SELF-ADHESIVE FIRE-EXTINGUISHING TAPE COMPRISING FIRE-EXTINGUISHING MICROCAPSULES, AND FIRE-EXTINGUISHING PRODUCT USING SAME 주식회사 지에프아이 2022-06-30 WO disclosed
US-20210238192-A1 VASCULAR ADHESION PROTEIN-1 (VAP-1) MODULATORS AND THERAPEUTIC USES THEREOF BLADE THERAPEUTICS, INC. 2021-08-05 US disclosed
EP-3235815-A1 AGENTS AGAINST PARASITIC HELMINTHS PHILIPPS-UNIVERSITÄT MARBURG (DE) 2017-10-25 EP disclosed
US-9169409-B2 Ink composition for imprint lithography and roll printing LG DISPLAY CO., LTD. (KR) 2015-10-27 US disclosed
WO-2015087857-A1 ARYL AMIDINE COMPOUND AND BACTERICIDAL AGENT 日本曹達株式会社 2015-06-18 WO disclosed
US-20100324001-A1 Novel Methods for the Treatment of Inflammatory Diseases CORTICAL PTY LTD (AU) 2010-12-23 US disclosed
WO-2010085664-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-29 WO disclosed
US-20100180947-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-22 US disclosed
CN-101735690-A Ink composition and method of fabricating liquid crystal display device using the same LG DISPLAY CO LTD 2010-06-16 CN disclosed
US-20100120181-A1 INK COMPOSITION AND METHOD OF FABRICATING LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME LG DISPLAY CO., LTD. (KR) 2010-05-13 US disclosed
US-20070021483-A1 Amidine derivatives for treating amyloidosis NEUROCHEM (INTERNATIONAL) LIMITED (CH) 2007-01-25 US disclosed
US-20070010563-A1 Novel methods for the treatment of inflammatory diseases CORTICAL PTY LTD (AU) 2007-01-11 US disclosed
US-20070010563-A1 Novel methods for the treatment of inflammatory diseases CORTICAL PTY LTD (AU) 2007-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210238192-A1 VASCULAR ADHESION PROTEIN-1 (VAP-1) MODULATORS AND THERAPEUTIC USES THEREOF VCAM1, VAPB, ICAM1 NISCH 4828/4885LMNA 3490/4885RECQL 4682/4885
US-20070010563-A1 Novel methods for the treatment of inflammatory diseases MIF, CCL2, CCL11 NISCH 1820/4885LMNA 3675/4885RECQL 3178/4885
US-20100324001-A1 Novel Methods for the Treatment of Inflammatory Diseases MIF, CCL2, CCL11 NISCH 1820/4885LMNA 3675/4885RECQL 3178/4885
US-20070021483-A1 Amidine derivatives for treating amyloidosis APP, IAPP, GRN NISCH 954/4885LMNA 685/4885RECQL 415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.