Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | VHL | P40337 | 1/20 | 0.36 |
| ▸ | ELOC | Q15369 | 1/20 | 0.36 |
| ▸ | ELOB | Q15370 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29059236 | 0.83 | ALOX5 (0.59) | APPALOX5HDAC2ACMSDBRAF | |
| SCHEMBL11786007 | 0.82 | TTR (0.47) | ALOX5ALOX15EGFR | |
| SCHEMBL6497283 | 0.82 | CYP3A4 (0.45) | KIF11CYP3A4APPALOX5BRAF | |
| SCHEMBL19111150 | 0.78 | KIF11 (0.43) | KIF11ERN1CYP3A4MKNK1MKNK2 | |
| SCHEMBL11310791 | 0.76 | MKNK1 (0.56) | KIF11ERN1MKNK1MKNK2HDAC2 | |
| SCHEMBL679970 | 0.76 | MKNK1 (0.56) | KIF11ERN1MKNK1MKNK2HDAC2 | |
| SCHEMBL19116666 | 0.76 | HSD17B1 (0.50) | CYP3A4APP | |
| SCHEMBL19100972 | 0.75 | CA1 (0.52) | CYP17A1APPBRAF | |
| SCHEMBL31274305 | 0.73 | TSHR (0.42) | KIF11MKNK1MKNK2HDAC2PDK2 | |
| SCHEMBL4289203 | 0.72 | MAPT (0.53) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9931379-B2 | Oxyntomodulin analogs and methods of making and using same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2018-04-03 | — | — | US | disclosed |
| US-20170196940-A1 | OXYNTOMODULIN ANALOGS AND METHODS OF MAKING AND USING SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-07-13 | — | — | US | disclosed |
| WO-2017075583-A2 | OXYNTOMODULIN ANALOGS AND METHODS OF MAKING AND USING SAME | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170196940-A1 | OXYNTOMODULIN ANALOGS AND METHODS OF MAKING AND USING SAME | PTMS, OGFRL1, SHBG | KIF11 3680/4885ERN1 3771/4885CYP3A4 4345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.