Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31508140 | 0.87 | ALDH1A1 (0.43) | PTGS1PTGS2ALDH1A1BACE1BACE2 | |
| SCHEMBL22289350 | 0.83 | PTGS1 (0.51) | PTGS1PTGS2ALDH1A1BACE1BACE2 | |
| SCHEMBL12355278 | 0.83 | PTGS1 (0.42) | PTGS1PTGS2ALDH1A1BACE1BACE2 | |
| SCHEMBL16513840 | 0.80 | HRH3 (0.50) | PTGS1PTGS2HRH3HTR2CHTR2B | |
| SCHEMBL24750246 | 0.79 | ALDH1A1 (0.51) | ALDH1A1CARM1PRMT1BACE1APP | |
| SCHEMBL18824873 | 0.77 | ATM (0.46) | PTGS1PTGS2ALDH1A1SCN9AHRH3 | |
| SCHEMBL12355288 | 0.77 | PTGS1 (0.46) | PTGS1PTGS2BACE1BACE2HRH3 | |
| SCHEMBL2397276 | 0.76 | CARM1 (0.47) | ALDH1A1CARM1PRMT1SCN9ABACE1 | |
| SCHEMBL12021829 | 0.76 | ALDH1A1 (0.39) | PTGS1PTGS2ALDH1A1BACE1BACE2 | |
| SCHEMBL4170069 | 0.75 | SLC6A3 (0.55) | HTR2ASLC6A2SLC6A4SLC6A3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10357035-B2 | Microbiocidal anilide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2019-07-23 | — | — | US | disclosed |
| US-20180317482-A1 | MICROBIOCIDAL ANILIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-11-08 | — | — | US | disclosed |
| EP-3371153-A1 | MICROBIOCIDAL ANILIDE DERIVATIVES | Syngenta Participations AG (CH) | 2018-09-12 | — | — | EP | disclosed |
| WO-2017076982-A1 | MICROBIOCIDAL ANILIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10357035-B2 | Microbiocidal anilide derivatives | MSR1, ARG1, ARG2 | PTGS1 1867/4885PTGS2 2864/4885ALDH1A1 396/4885 |
| US-20180317482-A1 | MICROBIOCIDAL ANILIDE DERIVATIVES | MSR1, ARG1, ARG2 | PTGS1 1867/4885PTGS2 2864/4885ALDH1A1 396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.