Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.91 |
| ▸ | CA2 | P00918 | 11/20 | 0.91 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.84 |
| ▸ | GAA | P10253 | 5/20 | 0.84 |
| ▸ | MAPT | P10636 | 5/20 | 0.84 |
| ▸ | GLA | P06280 | 3/20 | 0.84 |
| ▸ | HPGD | P15428 | 3/20 | 0.84 |
| ▸ | CFTR | P13569 | 1/20 | 0.84 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.84 |
| ▸ | ATM | Q13315 | 4/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | PDE5A | O76074 | 1/20 | 0.78 |
| ▸ | CDC42 | P60953 | 1/20 | 0.78 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.78 |
| ▸ | MMP2 | P08253 | 3/20 | 0.77 |
| ▸ | MMP9 | P14780 | 3/20 | 0.77 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.76 |
| ▸ | CA12 | O43570 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14484122 | 0.92 | CA1 (1.00) | CA1CA2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL18826376 | 0.88 | CA1 (0.91) | CA1CA2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL18826388 | 0.88 | CA1 (0.91) | CA1CA2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL18826372 | 0.88 | CA2 (0.79) | CA1CA2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL12494043 | 0.88 | L3MBTL1 (1.00) | CA1CA2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL8171059 | 0.85 | CA1 (0.73) | CA1CA2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL27760024 | 0.85 | EGFR (0.74) | CA1CA2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL15197341 | 0.83 | CA1 (1.00) | CA1CA2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL15197346 | 0.83 | CA2 (1.00) | CA1CA2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL5856383 | 0.83 | CA1 (0.67) | CA1CA2L3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9642835-B2 | Modulators of GTPase and use in relevant treatment | STC.UNM (US) | 2017-05-09 | — | — | US | disclosed |
| US-9642835-B2 | Modulators of GTPase and use in relevant treatment | STC.UNM (US) | 2017-05-09 | — | — | US | disclosed |