Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.79 |
| ▸ | CA1 | P00915 | 8/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.79 |
| ▸ | GAA | P10253 | 5/20 | 0.79 |
| ▸ | MAPT | P10636 | 5/20 | 0.79 |
| ▸ | HPGD | P15428 | 3/20 | 0.79 |
| ▸ | GLA | P06280 | 3/20 | 0.79 |
| ▸ | CFTR | P13569 | 1/20 | 0.79 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.79 |
| ▸ | ATM | Q13315 | 4/20 | 0.77 |
| ▸ | HTT | P42858 | 1/20 | 0.77 |
| ▸ | MMP2 | P08253 | 4/20 | 0.76 |
| ▸ | MMP9 | P14780 | 4/20 | 0.76 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.71 |
| ▸ | ACHE | P22303 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | CA12 | O43570 | 1/20 | 0.68 |
| ▸ | CA9 | Q16790 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14484122 | 0.89 | CA1 (1.00) | CA2CA1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL18826375 | 0.88 | CA1 (0.91) | CA2CA1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL18826392 | 0.87 | L3MBTL1 (1.00) | CA2CA1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL18826377 | 0.87 | L3MBTL1 (1.00) | CA2CA1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL18826389 | 0.87 | L3MBTL1 (1.00) | CA2CA1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL18826383 | 0.86 | PTGS2 (0.85) | CA2CA1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL15197346 | 0.82 | CA2 (1.00) | CA2CA1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL18826388 | 0.81 | CA1 (0.91) | CA2CA1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL18826376 | 0.81 | CA1 (0.91) | CA2CA1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL12494043 | 0.80 | L3MBTL1 (1.00) | CA2CA1L3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9642835-B2 | Modulators of GTPase and use in relevant treatment | STC.UNM (US) | 2017-05-09 | — | — | US | disclosed |
| US-9642835-B2 | Modulators of GTPase and use in relevant treatment | STC.UNM (US) | 2017-05-09 | — | — | US | disclosed |