Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19443974 | 0.81 | NPSR1 (0.41) | NPSR1ALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL23221638 | 0.80 | NPSR1 (0.38) | NPSR1ALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL18745271 | 0.79 | NPSR1 (0.48) | NPSR1ALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL21029199 | 0.79 | NPSR1 (0.40) | NPSR1ALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL18533863 | 0.76 | NPSR1 (0.38) | NPSR1ALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL19346868 | 0.76 | ALDH1A1 (0.37) | NPSR1ALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL19867963 | 0.75 | NPSR1 (0.36) | NPSR1ALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL379142 | 0.74 | TRPM8 (0.50) | NPSR1ALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL379140 | 0.74 | TRPM8 (0.50) | NPSR1ALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL26399527 | 0.74 | ALDH1A1 (0.35) | NPSR1ALDH1A1L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651862-B1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |