Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL379142 | 1.00 | TRPM8 (0.50) | TRPM8ALDH1A1TSHRAKR1C3NISCH | |
| SCHEMBL12411238 | 0.83 | LMNA (0.48) | TRPM8ALDH1A1TSHRAKR1C3NISCH | |
| SCHEMBL4445179 | 0.81 | NISCH (0.41) | TRPM8ALDH1A1TSHRAKR1C3NISCH | |
| SCHEMBL18745271 | 0.79 | NPSR1 (0.48) | TRPM8ALDH1A1TSHRNPSR1HTT | |
| SCHEMBL1123661 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TSHRAKR1C3NISCHFBP1 | |
| SCHEMBL7953400 | 0.76 | ALDH1A1 (0.41) | TRPM8ALDH1A1TSHRNPSR1HTT | |
| SCHEMBL18828477 | 0.74 | NPSR1 (0.43) | TRPM8ALDH1A1TSHRNPSR1HTT | |
| SCHEMBL27855636 | 0.74 | ALDH1A1 (0.56) | ALDH1A1TSHRAKR1C3FBP1KDM1A | |
| SCHEMBL19443974 | 0.72 | NPSR1 (0.41) | TRPM8ALDH1A1TSHRNPSR1HTT | |
| SCHEMBL12411254 | 0.72 | NPC1 (0.50) | ALDH1A1TSHRAKR1C3FBP1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009082-B1 | Synergistic lubricating oil composition containing a mixture of a nitro-substituted diarylamine and a diarylamine | CHEVRON ORONITE CO (US) | 2017-08-30 | — | — | EP | disclosed |
| US-8623798-B2 | Lubricating oil compositions containing a tetraalkyl-napthalene-1,8 diamine antioxidant | CHEVRON ORONITE COMPANY LLC (US) | 2014-01-07 | — | — | US | disclosed |
| EP-1801189-B1 | Synergistic lubricating oil composition containing a mixture of a benzo[b]perhydroheterocyclic arylamine and a diarylamine | CHEVRON ORONITE CO (US) | 2012-11-07 | — | — | EP | disclosed |
| EP-2077315-B1 | Lubricating oil compositions containing a tetraalkyl-napthalene-1,8 diamine antioxidant and a diarylamine antioxidant | CHEVRON ORONITE CO (US) | 2012-10-31 | — | — | EP | disclosed |
| EP-1801105-B1 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions | CHEVRON ORONITE CO (US) | 2012-01-25 | — | — | EP | disclosed |
| US-8003583-B2 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC (US) | 2011-08-23 | — | — | US | disclosed |
| EP-1801104-B1 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE CO (US) | 2011-01-05 | — | — | EP | disclosed |
| US-20100152079-A1 | LUBRICATING OIL COMPOSITIONS CONTAINING A TETRAALKYL-NAPTHALENE-1,8 DIAMINE ANTIOXIDANT | CHEVRON ORONITE COMPANY LLC | 2010-06-17 | — | — | US | disclosed |
| US-7683017-B2 | Synergistic lubricating oil composition containing a mixture of a nitro-substituted diarylamine and a diarylamine | CHEVRON ORONITE COMPANY LLC (US) | 2010-03-23 | — | — | US | disclosed |
| EP-2077315-A1 | Lubricating oil compositions containing a tetraalkyl-napthalene-1,8 diamine antioxidant | Chevron Oronite Company LLC (US) | 2009-07-08 | — | — | EP | disclosed |
| US-7501386-B2 | Lubricants for automotive and truck crankcase lubricants; as well as transmission lubricants, gear lubricants, hydraulic fluids, compressor oils, diesel and marine lubricants; superior oxidation inhibition; Phenyl-(1,2,3,4-tetrahydro-quinolin-6-yl)-amine, diphenylamine | CHEVRON ORONITE COMPANY, LLC (US) | 2009-03-10 | — | — | US | disclosed |
| EP-2009082-A2 | Synergistic lubricating oil composition containing a mixture of a nitro-substituted diarylamine and a diarylamine | Chevron Oronite Company LLC (US) | 2008-12-31 | — | — | EP | disclosed |
| US-20080318815-A1 | SYNERGISTIC LUBRICATING OIL COMPOSITION CONTAINING A MIXTURE OF A NITRO-SUBSTITUTED DIARYLAMINE AND A DAIRYLAMINE | CHEVRON ORONITE COMPANY LLC | 2008-12-25 | — | — | US | disclosed |
| US-7285518-B2 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC (US) | 2007-10-23 | — | — | US | disclosed |
| EP-1801104-A2 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | Chevron Oronite Company LLC (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1801105-A1 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions | Chevron Oronite Company LLC (US) | 2007-06-27 | — | — | EP | disclosed |
| EP-1801189-A2 | Synergistic lubricating oil composition containing a mixture of a benzo[b]perhydroheterocyclic arylamine and a diarylamine | Chevron Oronite Company LLC (US) | 2007-06-27 | — | — | EP | disclosed |
| US-20070142243-A1 | Synergistic lubricating oil composition containing a mixture of a benzo[b]perhydroheterocyclic arylamine and a diarylamine | CHEVRON ORONITE COMPANY LLC | 2007-06-21 | — | — | US | disclosed |
| US-20070142245-A1 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC | 2007-06-21 | — | — | US | disclosed |
| US-20070142246-A1 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | CHEVRON ORONITE COMPANY LLC | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142246-A1 | Benzo[b]perhydroheterocyclic arylamines and lubricating oil compositions | AHR, ARNT, HRH2 | TRPM8 2820/4885ALDH1A1 242/4885TSHR 4498/4885 |
| US-20070142245-A1 | Dibenzo[b]perhydroheterocyclic amines and lubricating oil compositions | ALOX12, ALOX15B, HRH1 | TRPM8 3288/4885ALDH1A1 417/4885TSHR 4444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.