SCHEMBL379142

SCHEMBL379142

CC(=Cc1ccccc1)N(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 3/20 0.50
ALDH1A1 P00352 3/20 0.47
TSHR P16473 1/20 0.47
AKR1C3 P42330 1/20 0.47
NISCH Q9Y2I1 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
FBP1 P09467 1/20 0.42
KDM1A O60341 1/20 0.40
RECQL P46063 1/20 0.40
HTT P42858 1/20 0.39
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
KMT2A Q03164 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NR1I2 O75469 1/20 0.38
RELA Q04206 1/20 0.38
GLA P06280 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL379140 1.00 TRPM8 (0.50) TRPM8ALDH1A1TSHRAKR1C3NISCH
SCHEMBL12411238 0.83 LMNA (0.48) TRPM8ALDH1A1TSHRAKR1C3NISCH
SCHEMBL4445179 0.81 NISCH (0.41) TRPM8ALDH1A1TSHRAKR1C3NISCH
SCHEMBL18745271 0.79 NPSR1 (0.48) TRPM8ALDH1A1TSHRNPSR1HTT
SCHEMBL1123661 0.77 ALDH1A1 (0.50) ALDH1A1TSHRAKR1C3NISCHFBP1
SCHEMBL7953400 0.76 ALDH1A1 (0.41) TRPM8ALDH1A1TSHRNPSR1HTT
SCHEMBL18828477 0.74 NPSR1 (0.43) TRPM8ALDH1A1TSHRNPSR1HTT
SCHEMBL27855636 0.74 ALDH1A1 (0.56) ALDH1A1TSHRAKR1C3FBP1KDM1A
SCHEMBL19443974 0.72 NPSR1 (0.41) TRPM8ALDH1A1TSHRNPSR1HTT
SCHEMBL12411254 0.72 NPC1 (0.50) ALDH1A1TSHRAKR1C3FBP1KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116410808-B Lubricating oil additive and lubricating oil 中国石油天然气股份有限公司 2025-01-28 CN claimed
CN-116333798-B Vacuum pump oil additive, vacuum pump oil and vacuum pump 中国石油天然气股份有限公司 2025-01-21 CN claimed
CN-118146860-A Lubricating oil composition for high-rotation-speed centrifugal compressor and application thereof 中国石油天然气股份有限公司 2024-06-07 CN claimed
CN-116410807-A Centrifugal compressor oil additive, centrifugal compressor oil and centrifugal compressor 中国石油天然气股份有限公司 2023-07-11 CN claimed
CN-116410808-A Lubricating oil additive and lubricating oil 中国石油天然气股份有限公司 2023-07-11 CN claimed
CN-116333798-A Vacuum pump oil additive, vacuum pump oil and vacuum pump 中国石油天然气股份有限公司 2023-06-27 CN claimed
CN-114854473-B Centrifugal compressor oil additive composition and application thereof 中国石油天然气股份有限公司 2023-04-25 CN claimed
CN-113881480-B Centrifugal compressor oil additive composition 中国石油天然气股份有限公司 2022-07-05 CN claimed
EP-1657293-B1 Diarylamine containing lubricating composition AFTON CHEMICAL CORP (US) 2017-10-11 EP claimed
US-8202829-B2 Lubricating composition AFTON CHEMICAL CORPORATION (US) 2012-06-19 US claimed
EP-1657293-A2 Diarylamine containing lubricating composition Afton Chemical Corporation (US) 2006-05-17 EP claimed
US-20060094607-A1 Lubricating composition AFTON CHEMICAL CORPORATION 2006-05-04 US claimed
CN-116410808-B Lubricating oil additive and lubricating oil 中国石油天然气股份有限公司 2025-01-28 CN disclosed
CN-116410807-B Centrifugal compressor oil additive, centrifugal compressor oil and centrifugal compressor 中国石油天然气股份有限公司 2025-01-28 CN disclosed
CN-116333798-B Vacuum pump oil additive, vacuum pump oil and vacuum pump 中国石油天然气股份有限公司 2025-01-21 CN disclosed
CN-118146860-A Lubricating oil composition for high-rotation-speed centrifugal compressor and application thereof 中国石油天然气股份有限公司 2024-06-07 CN disclosed
EP-1006173-A1 Lubricant compositions exhibiting extended oxidation stability ETHYL PETROLEUM ADDITIVES LIMITED (GB) 2000-06-07 EP disclosed
EP-0994175-A2 Turbine oils with excellent high temperature oxidative stability ETHYL CORPORATION (US) 2000-04-19 EP disclosed
EP-0892037-A1 Improved antioxidant system for lubrication base oils ETHYL CORPORATION (US) 1999-01-20 EP disclosed
US-5840672-A COMPRISING AT LEAST ONE SECONDARY DIARYLAMINE, AT LEAST ONE SULFURIZED OLEFIN AND/OR SULFURIZED HINDERED PHENOL AND AT LEAST ONE OIL SOLUBLE MOLYBDENUM COMPOUND; HIGHLY SATURATED, LOW SULFUR BASE OILS ETHYL CORPORATION (US) 1998-11-24 US disclosed