Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18831150 | 1.00 | SRC (0.44) | SRCGAALOXLOXL2MAPT | |
| SCHEMBL16303318 | 0.72 | TERT (0.38) | SRC | |
| SCHEMBL16292516 | 0.72 | TERT (0.38) | SRC | |
| SCHEMBL29956230 | 0.72 | ALDH1A1 (0.38) | LOXLOXL2ALDH1A1SMN1; SMN2 | |
| SCHEMBL20276120 | 0.72 | ALDH1A1 (0.38) | LOXLOXL2ALDH1A1SMN1; SMN2 | |
| SCHEMBL17984969 | 0.71 | MAP1LC3B (0.33) | MEN1KMT2A | |
| SCHEMBL12756953 | 0.69 | SRC (0.47) | SRCGAAMAPTLMNAALDH1A1 | |
| SCHEMBL1061501 | 0.68 | NOS2 (0.62) | LOXLOXL2MAPTALDH1A1NOS3 | |
| SCHEMBL9768798 | 0.68 | CYP1A2 (0.45) | GAAMAPTLMNANOS3NOS1 | |
| SCHEMBL27982847 | 0.68 | SRC (0.44) | SRCGAAMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650339-B2 | Inhibitors of histone demethylases | GILEAD SCIENCES, INC. (US) | 2017-05-16 | — | — | US | disclosed |