Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22590903 | 0.87 | HTT (0.40) | HTTAKR1B1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL18831572 | 0.84 | LMNA (0.33) | CYP3A4CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL18831729 | 0.84 | HPGD (0.31) | — | |
| SCHEMBL20686632 | 0.82 | GABRA1 (0.34) | CYP2C19HIF1ATAAR1GABRA1GABRB2 | |
| SCHEMBL20686703 | 0.82 | ALDH1A1 (0.33) | KMT2AMEN1AOC3SMN1; SMN2ALDH1A1 | |
| SCHEMBL21317949 | 0.80 | ALDH1A1 (0.36) | HIF1AHSD17B10AOC3MAPTALDH1A1 | |
| SCHEMBL19909873 | 0.79 | AOC3 (0.41) | HTTAKR1B1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL18831396 | 0.79 | POLQ (0.35) | CYP3A4MAPTTAAR1 | |
| SCHEMBL22038784 | 0.78 | HTR7 (0.41) | SMN1; SMN2 | |
| SCHEMBL18030820 | 0.78 | ALDH1A1 (0.40) | CYP3A4CYP2C9CYP2C19KMT2AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |
| EP-2900655-B1 | TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2017-05-10 | — | — | EP | disclosed |