Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.35 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1560997 | 0.88 | LPAR1 (0.74) | LPAR1GPR132 | |
| SCHEMBL18832675 | 0.87 | LPAR1 (0.61) | LPAR1HSP90AA1HSP90AB1GPR132NPC1 | |
| SCHEMBL18832654 | 0.87 | LPAR1 (0.63) | LPAR1NPC1RAB9A | |
| SCHEMBL18832663 | 0.87 | LPAR1 (0.43) | LPAR1HPGDMAPTLMNA | |
| SCHEMBL18832662 | 0.86 | LPAR1 (0.60) | LPAR1HSP90AA1HSP90AB1GPR132NPC1 | |
| SCHEMBL18832661 | 0.86 | LPAR1 (0.60) | LPAR1MAPTLMNASMN1; SMN2 | |
| SCHEMBL18832657 | 0.86 | LPAR1 (0.79) | LPAR1HSP90AA1HSP90AB1GPR132NPC1 | |
| SCHEMBL1561380 | 0.86 | LPAR1 (0.63) | LPAR1HSP90AA1HSP90AB1MRGPRX4GPR132 | |
| SCHEMBL18832658 | 0.85 | LPAR1 (0.58) | LPAR1MRGPRX4GPR132NPC1RAB9A | |
| SCHEMBL18832667 | 0.83 | LPAR1 (0.53) | LPAR1GPR132HPGDSIRT2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | claimed |