Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.58 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1560521 | 0.88 | LPAR1 (0.74) | LPAR1SCN9AGPR132 | |
| SCHEMBL18832675 | 0.87 | LPAR1 (0.61) | LPAR1GPR132NR1H4NPC1RAB9A | |
| SCHEMBL18832654 | 0.87 | LPAR1 (0.63) | LPAR1NPC1RAB9A | |
| SCHEMBL18832662 | 0.86 | LPAR1 (0.60) | LPAR1GPR132ALDH1A1NR1H4NPC1 | |
| SCHEMBL18832661 | 0.86 | LPAR1 (0.60) | LPAR1ALDH1A1 | |
| SCHEMBL18832657 | 0.86 | LPAR1 (0.79) | LPAR1GPR132NR1H4NPC1RAB9A | |
| SCHEMBL18832664 | 0.85 | LPAR1 (0.58) | LPAR1GPR132MRGPRX4HPGDNR1H4 | |
| SCHEMBL18832677 | 0.83 | LPAR1 (0.51) | LPAR1SCN9ANPC1RAB9A | |
| SCHEMBL18832666 | 0.82 | LPAR1 (0.53) | LPAR1GPR132NPC1RAB9ACYP1A2 | |
| SCHEMBL18832656 | 0.82 | LPAR1 (0.54) | LPAR1SCN9AGPR132 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | claimed |