Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561391 | 0.89 | LPAR1 (0.56) | LPAR1F10 | |
| SCHEMBL18832664 | 0.87 | LPAR1 (0.58) | LPAR1HPGDLMNAMAPT | |
| SCHEMBL18832675 | 0.76 | LPAR1 (0.61) | LPAR1 | |
| SCHEMBL1560997 | 0.75 | LPAR1 (0.74) | LPAR1 | |
| SCHEMBL18832654 | 0.74 | LPAR1 (0.63) | LPAR1 | |
| SCHEMBL18832668 | 0.73 | LPAR1 (0.46) | LPAR1KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL18832662 | 0.73 | LPAR1 (0.60) | LPAR1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL18832661 | 0.73 | LPAR1 (0.60) | LPAR1ALDH1A1LMNAMAPT | |
| SCHEMBL18832667 | 0.73 | LPAR1 (0.53) | LPAR1F10ALDH1A1HPGDLMNA | |
| SCHEMBL1561380 | 0.73 | LPAR1 (0.63) | LPAR1ALDH1A1LMNAMAPTSCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | claimed |