Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL17290171 | 0.85 | HTT (0.46) | HTTSNCAMAPTKMT2AHPGD | |
| SCHEMBL17476937 | 0.84 | ALDH1A1 (0.33) | HTTKMT2AHPGDMEN1KDM4E | |
| SCHEMBL16446549 | 0.82 | PDE4B (0.36) | HTTMAPTKMT2AHPGDLMNA | |
| SCHEMBL17290142 | 0.79 | ALDH1A1 (0.35) | HTTMAPTKMT2AHPGDLMNA | |
| SCHEMBL15921330 | 0.74 | ACHE (0.40) | MAPTKMT2ARAB9ASMN1; SMN2LMNA | |
| SCHEMBL15935755 | 0.71 | PDE4B (0.44) | HTTMAPTKMT2ASMN1; SMN2BCHE | |
| SCHEMBL29400863 | 0.71 | MAPT (0.50) | HTTSNCAMAPTKMT2AHPGD | |
| SCHEMBL4805235 | 0.70 | LMNA (0.52) | LMNAALDH1A1TP53L3MBTL1POLB | |
| SCHEMBL4023006 | 0.69 | ACHE (0.42) | MAPTKMT2AHPGDSMN1; SMN2LMNA | |
| SCHEMBL5734981 | 0.68 | ALDH1A1 (0.42) | HTTMAPTHPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2951173-B1 | NOVEL SUBSTITUTED CONDENSED PYRIMIDINE COMPOUNDS | GRUENENTHAL GMBH (DE) | 2017-05-17 | — | — | EP | disclosed |