Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | USP1 | O94782 | 1/20 | 0.32 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19375362 | 0.94 | MDM2 (0.32) | MDM2CHRM4CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL18834032 | 0.81 | MDM2 (0.36) | MDM2CHRM4CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL20432149 | 0.75 | CASR (0.33) | MDM2CSNK2A2CSNK2BCSNK2A1ABCG2 | |
| SCHEMBL18835220 | 0.73 | DPP4 (0.37) | MDM2SCN9AFFAR4HCRTR1HCRTR2 | |
| SCHEMBL19375085 | 0.72 | GFER (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL19375084 | 0.72 | MDM2 (0.34) | MDM2CHRM4USP1WDR48CSNK2A2 | |
| SCHEMBL18834648 | 0.68 | PDE5A (0.37) | CSNK2A2CSNK2BCSNK2A1ABCG2 | |
| SCHEMBL18835051 | 0.66 | TRPC4 (0.35) | — | |
| SCHEMBL16028967 | 0.66 | TRPC5 (0.58) | — | |
| SCHEMBL18833947 | 0.64 | PDE5A (0.37) | MDM2CHRM4DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |