Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18834032 | 0.84 | MDM2 (0.36) | CASRPPARGCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL18833700 | 0.75 | MDM2 (0.37) | CSNK2A2CSNK2BCSNK2A1ABCG2MDM2 | |
| SCHEMBL19375084 | 0.75 | MDM2 (0.34) | CASRCSNK2A2CSNK2BCSNK2A1ABCG2 | |
| SCHEMBL19375362 | 0.74 | MDM2 (0.32) | CSNK2A2CSNK2BCSNK2A1ABCG2MDM2 | |
| SCHEMBL18833947 | 0.72 | PDE5A (0.37) | CASRPPARGMDM2HPGDMCHR1 | |
| SCHEMBL18834648 | 0.71 | PDE5A (0.37) | CASRCSNK2A2CSNK2BCSNK2A1ABCG2 | |
| SCHEMBL19375085 | 0.64 | GFER (0.40) | KDM4EHPGDLMNAKMT2ANPSR1 | |
| SCHEMBL18834613 | 0.62 | SMN1; SMN2 (0.41) | CASRCSNK2A2CSNK2BCSNK2A1ABCG2 | |
| SCHEMBL16028050 | 0.61 | TRPC4 (0.52) | KDM4EHPGDTSHRLMNAMEN1 | |
| SCHEMBL19375382 | 0.61 | USP1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B3 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2018-08-01 | — | — | EP | disclosed |