Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.51 |
| ▸ | PNP | P00491 | 9/20 | 0.49 |
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20432204 | 0.88 | TYMS (0.47) | NOS1PNPTYMSXDH | |
| SCHEMBL4144591 | 0.80 | HPRT1 (0.50) | NOS1PNPTYMSQTRT1 | |
| SCHEMBL15026991 | 0.71 | SLC6A5 (0.44) | — | |
| SCHEMBL1062004 | 0.70 | PNP (0.43) | NOS1PNPTYMS | |
| SCHEMBL19204413 | 0.70 | NOS1 (0.47) | NOS1PNP | |
| SCHEMBL10506935 | 0.69 | MAPT (0.50) | PNPTYMSXDH | |
| SCHEMBL8912815 | 0.69 | TSHR (0.57) | PNPTYMS | |
| SCHEMBL9798195 | 0.69 | HPRT1 (0.47) | PNP | |
| SCHEMBL10508281 | 0.68 | HPRT1 (0.49) | PNPTYMSXDH | |
| SCHEMBL10506681 | 0.68 | HPRT1 (0.48) | NOS1PNPTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |