Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TYMS | P04818 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10648072 | 0.80 | DHFR (0.68) | HTTGAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8911693 | 0.77 | TTR (0.47) | TSHRALDH1A1 | |
| SCHEMBL11000972 | 0.77 | DRD4 (0.53) | TSHRMAPK1MEN1KMT2AHTT | |
| SCHEMBL8913183 | 0.77 | DHFR (0.44) | TYMS | |
| SCHEMBL8911701 | 0.75 | NOS1 (0.47) | MAPK1MEN1KMT2A | |
| SCHEMBL8912282 | 0.75 | DRD4 (0.43) | ALDH1A1KDM4EDRD4DRD2DRD3 | |
| SCHEMBL8912435 | 0.74 | DHFR (0.40) | TYMSATM | |
| SCHEMBL10653130 | 0.73 | LMNA (0.50) | TSHRMAPK1MEN1KMT2AHTT | |
| SCHEMBL10998482 | 0.72 | KMT2A (0.53) | TSHRMAPK1MEN1KMT2AHTT | |
| SCHEMBL10650805 | 0.71 | DRD4 (0.49) | TSHRMAPK1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670508-A | ANTITUMOR AGENTS FOR BRAIN TUMORS | NATIONAL SCIENCE COUNCIL (TW) | 1997-09-23 | — | — | US | disclosed |