Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | NEK4 | P51957 | 1/20 | 0.39 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18835186 | 0.83 | ALDH1A1 (0.38) | ALDH1A1ADRA2ACHEK1MAP4K4CHEK2 | |
| SCHEMBL18833721 | 0.82 | MEN1 (0.41) | ALDH1A1ADRA2ACHEK1MAP4K4CHEK2 | |
| SCHEMBL18834990 | 0.81 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNANPSR1MEN1 | |
| SCHEMBL18834573 | 0.77 | TRPC5 (0.51) | ALDH1A1ADRA2AMAPT | |
| SCHEMBL18833893 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNANPSR1MEN1 | |
| SCHEMBL15922546 | 0.69 | KMT2A (0.56) | ALDH1A1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL16028787 | 0.69 | ALDH1A1 (0.43) | ALDH1A1CHEK1MAP4K4CHEK2PRKCG | |
| SCHEMBL18835068 | 0.69 | ALDH1A1 (0.43) | ALDH1A1ADRA2AMAPTLMNANPSR1 | |
| SCHEMBL18834209 | 0.67 | ALDH1A1 (0.44) | ALDH1A1ADRA2ACHEK1MAP4K4CHEK2 | |
| SCHEMBL18834584 | 0.66 | TRPC5 (0.50) | ADRA2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970303-B1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES INC (US) | 2017-05-10 | — | — | EP | disclosed |